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Constitutively active rhodopsin and retinal diseaseChemistry of the retinoid (visual) cycleChemistry and biology of the initial steps in vision: the Friedenwald lecture.Molecular simulations and solid-state NMR investigate dynamical structure in rhodopsin activation.Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structuresInternal hydration increases during activation of the G-protein-coupled receptor rhodopsin.Development and application of hybrid structure based method for efficient screening of ligands binding to G-protein coupled receptors.How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.Retinal conformation and dynamics in activation of rhodopsin illuminated by solid-state H NMR spectroscopy.Sequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate.Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probesMolecular mechanism of long-range synergetic color tuning between multiple amino acid residues in conger rhodopsinGlutamic acid 181 is negatively charged in the bathorhodopsin photointermediate of visual rhodopsin.Low-Temperature Trapping of Photointermediates of the Rhodopsin E181Q Mutant.Role of bulk water in hydrolysis of the rhodopsin chromophore.Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes.Methodology of pulsed photoacoustics and its application to probe photosystems and receptors.Mechanism of signal propagation upon retinal isomerization: insights from molecular dynamics simulations of rhodopsin restrained by normal modesAtomistic insights into rhodopsin activation from a dynamic modelThermal stability of rhodopsin and progression of retinitis pigmentosa: comparison of S186W and D190N rhodopsin mutants.Two protonation switches control rhodopsin activation in membranesSolid-state 2H NMR spectroscopy of retinal proteins in aligned membranes.Dynamics of the internal water molecules in squid rhodopsin.6-s-cis Conformation and polar binding pocket of the retinal chromophore in the photoactivated state of rhodopsinStructural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes.Retinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy.Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.Lifting the lid on GPCRs: the role of extracellular loops.New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.Binding of rhodopsin and rhodopsin analogues to transducin, rhodopsin kinase and arrestin-1.Retinal Conformation Changes Rhodopsin's Dynamic Ensemble.Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.Dynamic structure of retinylidene ligand of rhodopsin probed by molecular simulationsProtein Field Effect on the Dark State of 11-cis Retinal in Rhodopsin by Quantum Monte Carlo/Molecular Mechanics.Structural impact of the E113Q counterion mutation on the activation and deactivation pathways of the G protein-coupled receptor rhodopsin.Structural transitions of transmembrane helix 6 in the formation of metarhodopsin I.Model of Abnormal Chromophore-Protein Interaction for Е181К Rhodopsin Mutation: Computer Molecular Dynamics StudyLight activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints.Explaining the mobility of retinal in activated rhodopsin and opsin.Continuum Electrostatic Calculation on Bovine Rhodopsin: Protonation and the Effect of the Membrane Potential.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
The role of Glu181 in the photoactivation of rhodopsin.
@en
The role of Glu181 in the photoactivation of rhodopsin.
@nl
type
label
The role of Glu181 in the photoactivation of rhodopsin.
@en
The role of Glu181 in the photoactivation of rhodopsin.
@nl
prefLabel
The role of Glu181 in the photoactivation of rhodopsin.
@en
The role of Glu181 in the photoactivation of rhodopsin.
@nl
P2093
P1476
The role of Glu181 in the photoactivation of rhodopsin.
@en
P2093
Elsa C Y Yan
Friedrich Siebert
Mareike Beck
Reiner Vogel
P304
P356
10.1016/J.JMB.2005.08.039
P407
P577
2005-10-01T00:00:00Z