Multifunctional roles of the conserved Arg residues in the second region of homology of p97/valosin-containing protein.
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The Oligomeric State of the Active Vps4 AAA ATPaseAltered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 MutantsThe Vps4 C-terminal helix is a critical determinant for assembly and ATPase activity and has elements conserved in other members of the meiotic clade of AAA ATPases.Physical and genetic associations of the Irc20 ubiquitin ligase with Cdc48 and SUMO.Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformationRoles of conserved arginines in ATP-binding domains of AAA+ chaperone ClpB from Thermus thermophilusAnalysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPaseQuantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.Dissecting the N-ethylmaleimide-sensitive factor: required elements of the N and D1 domainsPathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD modelStructure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocationThe molecular architecture of the metalloprotease FtsH.trans-Acting arginine residues in the AAA+ chaperone ClpB allosterically regulate the activity through inter- and intradomain communication.Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region.Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligaseDynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission.Functional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machineRole of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain.An Afg2/Spaf-related Cdc48-like AAA ATPase regulates the stability and activity of the C. elegans Aurora B kinase AIR-2ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF).Structure and Function of p97 and Pex1/6 Type II AAA+ Complexes.Conserved motifs involved in ATP hydrolysis by MalT, a signal transduction ATPase with numerous domains from Escherichia coli.Mutant Analysis Reveals Allosteric Regulation of ClpB DisaggregaseAllelic Expression Imbalance Promoting a Mutant PEX6 Allele Causes Zellweger Spectrum Disorder.
P2860
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P2860
Multifunctional roles of the conserved Arg residues in the second region of homology of p97/valosin-containing protein.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Multifunctional roles of the c ...... 97/valosin-containing protein.
@en
Multifunctional roles of the c ...... 97/valosin-containing protein.
@nl
type
label
Multifunctional roles of the c ...... 97/valosin-containing protein.
@en
Multifunctional roles of the c ...... 97/valosin-containing protein.
@nl
prefLabel
Multifunctional roles of the c ...... 97/valosin-containing protein.
@en
Multifunctional roles of the c ...... 97/valosin-containing protein.
@nl
P2093
P2860
P356
P1476
Multifunctional roles of the c ...... 97/valosin-containing protein.
@en
P2093
Changcheng Song
Chou-Chi H Li
Lauren Irizarry
Renming Dai
Xiaodong Zhang
P2860
P304
40515-40523
P356
10.1074/JBC.M509636200
P407
P577
2005-10-10T00:00:00Z