Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain.
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Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2Protein isoaspartate methyltransferase prevents apoptosis induced by oxidative stress in endothelial cells: role of Bcl-Xl deamidation and methylationIntegrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice.Alcohol-related brain damage in humans.Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning.Isoaspartyl formation in creatine kinase B is associated with loss of enzymatic activity; implications for the linkage of isoaspartate accumulation and neurological dysfunction in the PIMT knockout mouse.Are ancient proteins responsible for the age-related decline in health and fitness?Exercise protects against MPTP-induced neurotoxicity in mice.Considerations in the identification of endogenous substrates for protein L-isoaspartyl methyltransferase: the case of synuclein.Mass spectrometric peptide analysis of 2DE-separated mouse spinal cord and rat hippocampus proteins suggests an NGxG motif of importance for in vivo deamidation.Molecular ageing of alpha- and Beta-synucleins: protein damage and repair mechanisms.Uses of phage display in agriculture: a review of food-related protein-protein interactions discovered by biopanning over diverse baitsMass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides.Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent.Accelerated protein damage in brains of PIMT+/- mice; a possible model for the variability of cognitive decline in human agingPost-translational modification and regulation of actin.Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer's Disease: Comparison and Contrast with Microtubule-Associated Protein TauPosttranslational Protein Modifications in Type 1 Diabetes - Genetic Studies with PCMT1, the Repair Enzyme Protein Isoaspartate Methyltransferase (PIMT) Encoding GeneBrain proteomics supports the role of glutamate metabolism and suggests other metabolic alterations in protein l-isoaspartyl methyltransferase (PIMT)-knockout miceToward proteome-scale identification and quantification of isoaspartyl residues in biological samples.The V119I polymorphism in protein L-isoaspartate O-methyltransferase alters the substrate-binding interface.Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling.Isoaspartyl protein damage and repair in mouse retina.Collapsin response mediator protein-2: an emerging pathologic feature and therapeutic target for neurodisease indications.Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4.Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain.Defective responses to oxidative stress in protein l-isoaspartyl repair-deficient Caenorhabditis elegans.Enzymatic attributes of an l-isoaspartyl methyltransferase from Candida utilis and its role in cell survival.A missense mutation in ASRGL1 is involved in causing autosomal recessive retinal degeneration.Polymorphic Variants of Human Protein l-Isoaspartyl Methyltransferase Affect Catalytic Activity, Aggregation, and Thermal Stability: IMPLICATIONS FOR THE ETIOLOGY OF NEUROLOGICAL DISORDERS AND COGNITIVE AGING.Accumulation of altered aspartyl residues in erythrocyte proteins from patients with Down's syndrome.New findings on SNP variants of human protein L-isoaspartyl methyltransferase that affect catalytic activity, thermal stability, and aggregation.Implications of Metal Binding and Asparagine Deamidation for Amyloid Formation
P2860
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P2860
Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Protein repair in the brain, p ...... hyltransferase in mouse brain.
@en
Protein repair in the brain, p ...... hyltransferase in mouse brain.
@nl
type
label
Protein repair in the brain, p ...... hyltransferase in mouse brain.
@en
Protein repair in the brain, p ...... hyltransferase in mouse brain.
@nl
prefLabel
Protein repair in the brain, p ...... hyltransferase in mouse brain.
@en
Protein repair in the brain, p ...... hyltransferase in mouse brain.
@nl
P2093
P2860
P356
P1476
Protein repair in the brain, p ...... hyltransferase in mouse brain.
@en
P2093
Dana W Aswad
Hester A Doyle
Jeff X Zhu
Mark J Mamula
P2860
P304
33802-33813
P356
10.1074/JBC.M606958200
P407
P577
2006-09-07T00:00:00Z