Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo.

Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo.

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http://www.wikidata.org/entity/Q46755005
Development of a genotyping tool for a functionally relevant CYP2C19 allele (Phe100Asn, Ala103Val and Ile112Leu) in cynomolgus macaques.Development of genotyping method for functionally relevant variants of cytochromes P450 in cynomolgus macaques.Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers.Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies.Efavirenz clearances in vitro and in vivo in six cynomolgus monkeys associated with polymorphic cytochrome P450 2C9 and simulated by individual physiologically based pharmacokinetic models.Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models.Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19.R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys.In vivo individual variations in pharmacokinetics of efavirenz in cynomolgus monkeys genotyped for cytochrome P450 2C9.
P2860

Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo.

Item
http://www.wikidata.org/entity/Q46755005
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-my
2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Slow R-warfarin 7-hydroxylatio ...... in cynomolgus monkeys in vivo.
@en
Slow R-warfarin 7-hydroxylatio ...... in cynomolgus monkeys in vivo.
@nl
type
label
Slow R-warfarin 7-hydroxylatio ...... in cynomolgus monkeys in vivo.
@en
Slow R-warfarin 7-hydroxylatio ...... in cynomolgus monkeys in vivo.
@nl
prefLabel
Slow R-warfarin 7-hydroxylatio ...... in cynomolgus monkeys in vivo.
@en
Slow R-warfarin 7-hydroxylatio ...... in cynomolgus monkeys in vivo.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Slow R-warfarin 7-hydroxylatio ...... in cynomolgus monkeys in vivo
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698