Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
about
Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarityEpithelial cell polarity: a major gatekeeper against cancer?Cell polarity signaling in the plasticity of cancer cell invasivenessRho GTPases in collective cell migrationCompetition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.Mechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapsesInvolvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarityAstrocyte stellation, a process dependent on Rac1 is sustained by the regulated exocytosis of enlargeosomesInvolvement of Girdin in the determination of cell polarity during cell migrationSpatial regulation of VEGF receptor endocytosis in angiogenesisPar3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migrationRandom versus directionally persistent cell migrationThe interdependence of the Rho GTPases and apicobasal cell polarity.Signaling pathways in cell polarity.Phosphorylation of the par polarity complex protein Par3 at serine 962 is mediated by aurora a and regulates its function in neuronal polarity.Widely conserved signaling pathways in the establishment of cell polarityCollective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation.Microtubule remodelling is required for the front-rear polarity switch during contact inhibition of locomotionVesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration.Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries.Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion.Evidence for the involvement of Lfc and Tctex-1 in axon formationThe PAR complex controls the spatiotemporal dynamics of F-actin and the MTOC in directionally migrating leukocytes.Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse.A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium.Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration.Discovery of long-range inhibitory signaling to ensure single axon formation.From cells to organs: building polarized tissue.Rho-associated protein kinase modulates neurite extension by regulating microtubule remodeling and vinculin distribution.Protein complexes that control renal epithelial polarity.Bazooka mediates secondary axon morphology in Drosophila brain lineages.PAR3 and aPKC regulate Golgi organization through CLASP2 phosphorylation to generate cell polarity.Phosphoinositides in cell architecture.Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst.ROCK1-directed basement membrane positioning coordinates epithelial tissue polarity.ROCK1 feedback regulation of the upstream small GTPase RhoARadial Glial Cell-Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact SiteTiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration
P2860
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P2860
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
@en
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
@nl
type
label
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
@en
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
@nl
prefLabel
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
@en
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.
@nl
P2093
P1433
P1476
Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation
@en
P2093
Kozo Kaibuchi
Masanori Nakayama
Masayuki Sugimoto
Sigeo Ohno
Takaaki M Goto
Takafumi Shinagawa
P304
P356
10.1016/J.DEVCEL.2007.11.021
P407
P577
2008-02-01T00:00:00Z