Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.
about
Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activationLack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasisCo-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteinsDiscoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signalingDynamics of cell polarity in tissue morphogenesis: a comparative view from Drosophila and CionaDiscoidin Domain Receptors: Potential Actors and Targets in CancerCell polarity signaling in the plasticity of cancer cell invasivenessRho GTPase signalling in cell migrationSearching novel diagnostic markers and targets for therapy of CKDEpithelia migration: a spatiotemporal interplay between contraction and adhesionA tale of two collagen receptors, integrin β1 and discoidin domain receptor 1, in epithelial cell differentiationRemodelling the extracellular matrix in development and diseaseRho GTPases in collective cell migrationDynamic myosin activation promotes collective morphology and migration by locally balancing oppositional forces from surrounding tissue.P-cadherin promotes collective cell migration via a Cdc42-mediated increase in mechanical forcesPolarized E-cadherin endocytosis directs actomyosin remodeling during embryonic wound repair.Advancing Edge Speeds of Epithelial Monolayers Depend on Their Initial Confining GeometryStimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasionThe cell surface mucin podocalyxin regulates collective breast tumor budding.Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.The Mammalian Blood-Testis Barrier: Its Biology and RegulationRnd3 as a Novel Target to Ameliorate Microvascular Leakagep120-catenin is essential for terminal end bud function and mammary morphogenesis.Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility.Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development.The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells.Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.Optical regulation of cell chain.Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K.Discoidin domain receptors in disease.Discoidin domain receptor functions in physiological and pathological conditions.FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway.Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformationMutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters.Long-term culture of human breast cancer specimens and their analysis using optical projection tomography.Signaling network state predicts twist-mediated effects on breast cell migration across diverse growth factor contexts.Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin.
P2860
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P2860
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Collective cell migration requ ...... rity regulators Par3 and Par6.
@ast
Collective cell migration requ ...... rity regulators Par3 and Par6.
@en
type
label
Collective cell migration requ ...... rity regulators Par3 and Par6.
@ast
Collective cell migration requ ...... rity regulators Par3 and Par6.
@en
prefLabel
Collective cell migration requ ...... rity regulators Par3 and Par6.
@ast
Collective cell migration requ ...... rity regulators Par3 and Par6.
@en
P2093
P2860
P356
P1433
P1476
Collective cell migration requ ...... rity regulators Par3 and Par6.
@en
P2093
Birgit Leitinger
Cristina Hidalgo-Carcedo
Kevin Harrington
Peter Williamson
Shahid I Chaudhry
Steven Hooper
P2860
P2888
P356
10.1038/NCB2133
P50
P577
2010-12-19T00:00:00Z
P5875
P6179
1005183863