The PTPN22 1858T gene variant in type 1 diabetes is associated with reduced residual beta-cell function and worse metabolic control.
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Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association StudiesThe PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes.Temporal trends of HLA, CTLA-4 and PTPN22 genotype frequencies among type 1 diabetes in Continental Italy.Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual β-cell function 1 year after diagnosis of type 1 diabetes.Effect of the PTPN22 and INS risk genotypes on the progression to clinical type 1 diabetes after the initiation of β-cell autoimmunityThe metabolic progression to type 1 diabetes as indicated by serial oral glucose tolerance testing in the Diabetes Prevention Trial-type 1.Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic ControlDo non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?C-peptide in the natural history of type 1 diabetesDiaPep277 peptide therapy in the context of other immune intervention trials in type 1 diabetes.Role of the C1858T polymorphism of protein tyrosine phosphatase non-receptor type 22 (PTPN22) in children and adolescents with type 1 diabetes.C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes?HLA-DR, HLA-DQB1 and PTPN22 gene polymorphism: association with age at onset for autoimmune diabetes.Etiopathogenesis of type 1 diabetes mellitus: prognostic factors for the evolution of residual beta cell function.Serum titres of anti-glutamic acid decarboxylase-65 and anti-IA-2 autoantibodies are associated with different immunoregulatory milieu in newly diagnosed type 1 diabetes patients.Coincidence of PTPN22 c.1858CC and FCRL3 -169CC genotypes as a biomarker of preserved residual β-cell function in children with type 1 diabetes.
P2860
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P2860
The PTPN22 1858T gene variant in type 1 diabetes is associated with reduced residual beta-cell function and worse metabolic control.
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2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
The PTPN22 1858T gene variant ...... n and worse metabolic control.
@en
The PTPN22 1858T gene variant ...... n and worse metabolic control.
@nl
type
label
The PTPN22 1858T gene variant ...... n and worse metabolic control.
@en
The PTPN22 1858T gene variant ...... n and worse metabolic control.
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The PTPN22 1858T gene variant ...... n and worse metabolic control.
@en
The PTPN22 1858T gene variant ...... n and worse metabolic control.
@nl
P2093
P356
P1433
P1476
The PTPN22 1858T gene variant ...... n and worse metabolic control.
@en
P2093
Antonio Petrone
Immunotherapy Diabetes (IMDIAB) Group
John Osborn
Marco Capizzi
Marialuisa Spoletini
Paolo Pozzilli
Sara Zavarella
Simona Zampetti
P304
P356
10.2337/DC07-1158
P407
P577
2008-02-05T00:00:00Z