Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
about
Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese miceA novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits.11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.Hyperglycemia induces the variations of 11β-hydroxysteroid dehydrogenase type 1 and peroxisome proliferator-activated receptor-γ expression in hippocampus and hypothalamus of diabetic rats.11β-HSD1 inhibition ameliorates diabetes-induced cardiomyocyte hypertrophy and cardiac fibrosis through modulation of EGFR activity.Protective effects of carbenoxolone, an 11β-HSD1 inhibitor, against chemical induced dry eye syndrome.Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice.
P2860
Q24627436-1915CDDC-0EA2-4969-8E96-7C045EB07344Q34023395-1083510A-4E34-44C9-92E2-2E80C6616CC6Q34253331-439A41EA-66CA-4841-A4BA-D7EF5672652AQ42225428-6D6900D4-37FE-4A0C-9BEE-2F3B6ABA9BCDQ47094783-9B43F4AF-8FF9-479E-8547-1A5D73BC8C40Q50193141-AC83CDB4-F4C0-4686-BD9C-E10174FA27E6Q51392149-949DB2D5-6753-4657-9FA1-5D3BC81E18FC
P2860
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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name
Sub-chronic administration of ...... ice with diet-induced obesity.
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Sub-chronic administration of ...... ice with diet-induced obesity.
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type
label
Sub-chronic administration of ...... ice with diet-induced obesity.
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Sub-chronic administration of ...... ice with diet-induced obesity.
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Sub-chronic administration of ...... ice with diet-induced obesity.
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Sub-chronic administration of ...... ice with diet-induced obesity.
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Sub-chronic administration of ...... ice with diet-induced obesity.
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Aine M McKillop
Ashley Taylor
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10.1515/BC.2008.049
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2008-04-01T00:00:00Z