Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice model.
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Imeglimin: A Potential New Multi-Target Drug for Type 2 DiabetesUpdate on the treatment of type 2 diabetes mellitusShort-term and long-term effects of submaximal maternal exercise on offspring glucose homeostasis and pancreatic function.Reduced mitochondrial mass and function add to age-related susceptibility toward diet-induced fatty liver in C57BL/6J mice.Liver mitochondrial function in ZDF rats during the early stages of diabetes disease.Investigational insulin secretagogues for type 2 diabetes.Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents.Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.Preventing cell death with a 'check valve' in mitochondrial complex I?Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells.Maternal exercise modifies body composition and energy substrates handling in male offspring fed a high-fat/high-sucrose diet.Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance
P2860
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P2860
Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice model.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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name
Imeglimin normalizes glucose t ...... high-sucrose diet mice model.
@en
Imeglimin normalizes glucose t ...... high-sucrose diet mice model.
@nl
type
label
Imeglimin normalizes glucose t ...... high-sucrose diet mice model.
@en
Imeglimin normalizes glucose t ...... high-sucrose diet mice model.
@nl
prefLabel
Imeglimin normalizes glucose t ...... high-sucrose diet mice model.
@en
Imeglimin normalizes glucose t ...... high-sucrose diet mice model.
@nl
P2093
P50
P356
P1433
P1476
Imeglimin normalizes glucose t ...... high-sucrose diet mice model.
@en
P2093
Anne-Marie Madec
Annie Durand
Cécile Acquaviva
Emmanuelle Meugnier
Jean-Paul Pais de Barros
Marie-Agnès Chauvin
Nadia Bendridi
Nathalie Bernoud-Hubac
Sophie Hallakou-Bozec
Sébastien Bolze
P304
P356
10.2337/DB14-1220
P407
P577
2014-12-31T00:00:00Z