Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not of pravastatin.
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The relationships of markers of cholesterol homeostasis with carotid intima-media thicknessDifferential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- miceManagement of intracerebral hemorrhage--use of statinsEffects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 miceCholesterol-modifying strategies for Alzheimer's disease.Lovastatin inhibits VEGFR and AKT activation: synergistic cytotoxicity in combination with VEGFR inhibitorsAssociation of Cognitive Impairment in Patients on 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase InhibitorsStatins and neuroprotection: a prescription to move the field forwardApoE and cholesterol in schizophrenia and bipolar disorder: comparison of grey and white matter and relation with APOE genotypeCognitive Impairment and Age-Related Vision Disorders: Their Possible Relationship and the Evaluation of the Use of Aspirin and Statins in a 65 Years-and-Over Sardinian PopulationLong-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action.Molecular mechanisms underlying the effects of statins in the central nervous system.Chronic pravastatin but not atorvastatin treatment impairs cognitive function in two rodent models of learning and memoryRoles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains.Acute intake of plant stanol esters induces changes in lipid and lipoprotein metabolism-related gene expression in the liver and intestines of mice.Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.Cholesterol level influences opioid signaling in cell models and analgesia in mice and humans.Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans.Effects of Dietary Plant Sterols and Stanol Esters with Low- and High-Fat Diets in Chronic and Acute Models for Experimental ColitisCholesterol: its regulation and role in central nervous system disorders.Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study.Prevention approaches in a preclinical canine model of Alzheimer's disease: benefits and challenges.Therapeutic interventions targeting Beta amyloid pathogenesis in an aging dog model.A canine model of human aging and Alzheimer's disease.Is there a role for statins in fungal infections?Statins more than cholesterol lowering agents in Alzheimer disease: their pleiotropic functions as potential therapeutic targets.Mechanisms, treatment and prevention of cellular injury and death from delayed events after aneurysmal subarachnoid hemorrhage.Statins and neuroprotection: basic pharmacology needed.ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.Current drug treatment of hyperlipidemia in older adults.Can LDL cholesterol be too low? Possible risks of extremely low levels.Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.Apolipoprotein B100 secretion by cultured ARPE-19 cells is modulated by alteration of cholesterol levels.A specific inhibitor of cholesterol biosynthesis, BM15.766, reduces the expression of beta-secretase and the production of amyloid-beta in vitro.Platelet-activating factor antagonists enhance intracellular degradation of amyloid-β42 in neurons via regulation of cholesterol ester hydrolases.HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival.Statins enhance formation of phagocyte extracellular traps.Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosisImpact of a multi-nutrient diet on cognition, brain metabolism, hemodynamics, and plasticity in apoE4 carrier and apoE knockout mice.
P2860
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P2860
Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not of pravastatin.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Brain cholesterol synthesis in ...... statin but not of pravastatin.
@en
Brain cholesterol synthesis in ...... statin but not of pravastatin.
@nl
type
label
Brain cholesterol synthesis in ...... statin but not of pravastatin.
@en
Brain cholesterol synthesis in ...... statin but not of pravastatin.
@nl
prefLabel
Brain cholesterol synthesis in ...... statin but not of pravastatin.
@en
Brain cholesterol synthesis in ...... statin but not of pravastatin.
@nl
P2093
P356
P1476
Brain cholesterol synthesis in ...... statin but not of pravastatin.
@en
P2093
Dieter Lütjohann
Karin M Thelen
Katharina M Rentsch
Maria Olin
Maura Heverin
Ulla Andersson
Ursula Gutteck
P304
P356
10.1124/JPET.105.094136
P407
P577
2005-11-10T00:00:00Z