Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action.
about
Targeting membrane androgen receptors in tumorsDHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptorsHuman uterine smooth muscle and leiomyoma cells differ in their rapid 17beta-estradiol signaling: implications for proliferationThe role of estrogen and androgen receptors in bone health and diseaseToxicity testing in the 21st century: a vision and a strategyExtranuclear functions of ER impact invasive migration and metastasis by breast cancer cellsThe estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical boneThe roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cellsNitric oxide-sensitive guanylyl cyclase is differentially regulated by nuclear and non-nuclear estrogen pathways in anterior pituitary glandDesign of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissuesNovel actions of estrogen to promote proliferation: integration of cytoplasmic and nuclear pathways.Membrane initiated estrogen signaling in breast cancer.Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions.KBERG: KnowledgeBase for Estrogen Responsive Genes.Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus.Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activationGPR30 mediates estrogen rapid signaling and neuroprotection.Mechanisms of estrogen signaling and gene expression via GPR30Modulation of human estrogen receptor α activity by multivalent estradiol-peptidomimetic conjugates.Synthesis and characterization of fluorescent 4-hydroxytamoxifen conjugates with unique antiestrogenic propertiesEstrogen increases ENaC activity via PKCδ signaling in renal cortical collecting duct cells.Cyclin D1 integrates estrogen-mediated DNA damage repair signaling.Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membraneNon-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.Rapid progress for non-nuclear estrogen receptor signalingClick synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogensRecent discoveries on the control of gonadotrophin-releasing hormone neurones in nonhuman primatesEvaluation of a luciferase-based reporter assay as a screen for inhibitors of estrogen-ERα-induced proliferation of breast cancer cells.Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis.Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.Development of subtype-selective oestrogen receptor-based therapeutics.Topical KGF treatment as a therapeutic strategy for vaginal atrophy in a model of ovariectomized mice.Regulation of endogenous conductances in GnRH neurons by estrogensGenomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs.Estrogens and Androgens in Skeletal Physiology and Pathophysiology.Minireview: Extranuclear steroid receptors: roles in modulation of cell functions.Membrane estrogen receptors mediate calcium signaling and MAP kinase activation in individual hippocampal neurons.Selective mutations in estrogen receptor alpha D-domain alters nuclear translocation and non-estrogen response element gene regulatory mechanisms.Non-nuclear estrogen receptor signaling in the endothelium.
P2860
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P2860
Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Estrogen dendrimer conjugates ...... c pathways of estrogen action.
@en
Estrogen dendrimer conjugates ...... c pathways of estrogen action.
@nl
type
label
Estrogen dendrimer conjugates ...... c pathways of estrogen action.
@en
Estrogen dendrimer conjugates ...... c pathways of estrogen action.
@nl
prefLabel
Estrogen dendrimer conjugates ...... c pathways of estrogen action.
@en
Estrogen dendrimer conjugates ...... c pathways of estrogen action.
@nl
P2093
P356
P1476
Estrogen dendrimer conjugates ...... c pathways of estrogen action.
@en
P2093
Cory C Funk
John A Katzenellenbogen
Rachel Schiff
Sung Hoon Kim
William R Harrington
P304
P356
10.1210/ME.2005-0186
P577
2005-11-23T00:00:00Z