Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell.
about
Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cellsUp on the tightrope: natural killer cell activation and inhibitionCD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27kip1 signaling.Differential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes.SHIP1 inhibition increases immunoregulatory capacity and triggers apoptosis of hematopoietic cancer cells.TGF-β1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistenceDiscovery and development of small molecule SHIP phosphatase modulators.Inositol phospholipid signaling and the biology of natural killer cells.Therapeutic potential of SH2 domain-containing inositol-5'-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancerMouse natural killer cell development and maturation are differentially regulated by SHIP-1.Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signalingRecruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells.A role for SHIP in stem cell biology and transplantation.Tolerance and reactivity of NK cells: two sides of the same coin?Inhibitor and activator: dual functions for SHIP in immunity and cancer.Role of inositol phospholipid signaling in natural killer cell biology.Role of SHIP1 in cancer and mucosal inflammation.Role of inositol poly-phosphatases and their targets in T cell biology.Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target.NK cell education via nonclassical MHC and non-MHC ligands.Lineage extrinsic and intrinsic control of immunoregulatory cell numbers by SHIP.SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicansHomotypic cell to cell cross-talk among human natural killer cells reveals differential and overlapping roles of 2B4 and CD2.SHIP1 intrinsically regulates NK cell signaling and education, resulting in tolerance of an MHC class I-mismatched bone marrow graft in micePharmacological targeting of phosphoinositide lipid kinases and phosphatases in the immune system: success, disappointment, and new opportunities.The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function.Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides.Importance and mechanism of 'switch' function of SAP family adapters.
P2860
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P2860
Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Inappropriate recruitment and ...... in the SHIP-deficient NK cell.
@en
Inappropriate recruitment and ...... omain-containing phosphatase 1
@nl
type
label
Inappropriate recruitment and ...... in the SHIP-deficient NK cell.
@en
Inappropriate recruitment and ...... omain-containing phosphatase 1
@nl
prefLabel
Inappropriate recruitment and ...... in the SHIP-deficient NK cell.
@en
Inappropriate recruitment and ...... omain-containing phosphatase 1
@nl
P2093
P1476
Inappropriate recruitment and ...... in the SHIP-deficient NK cell.
@en
P2093
Harshani R Lawrence
Joseph A Wahle
Kim H T Paraiso
Liwei Chen
Robert D Kendig
P304
P356
10.4049/JIMMUNOL.179.12.8009
P407
P577
2007-12-01T00:00:00Z