Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.
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Sulforaphane inhibits prostaglandin E2 synthesis by suppressing microsomal prostaglandin E synthase 1.Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axisCyclic compressive loading on 3D tissue of human synovial fibroblasts upregulates prostaglandin E2 via COX-2 production without IL-1β and TNF-αHIF-1α inhibition reduces nasal inflammation in a murine allergic rhinitis modelThe Transient Chondrocyte Phenotype in Human Osteophytic Cartilage: A Role of Pigment Epithelium-Derived Factor?Polymorphic variation of hypoxia inducible factor-1 A (HIF1A) gene might contribute to the development of knee osteoarthritis: a pilot study.Hypoxia-inducible factor-2α is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer.A mouse strain less responsive to dioxin-induced prostaglandin E2 synthesis is resistant to the onset of neonatal hydronephrosis.Role of hypoxia-inducible factor 1 alpha in the integrity of articular cartilage in murine knee jointsMicrosomal prostaglandin e synthase-1 in rheumatic diseases.Role of HIF-1α signaling pathway in Osteoarthritis: a systematic review.PEDF Is Associated with the Termination of Chondrocyte Phenotype and Catabolism of Cartilage Tissue.Deletion of the oxygen-dependent degradation domain results in impaired transcriptional activity of hypoxia-inducible factors.Dynamic compression combined with SOX-9 overexpression in rabbit adipose-derived mesenchymal stem cells cultured in a three-dimensional gradual porous PLGA composite scaffold upregulates HIF-1α expression.Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytesProlyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.Haem oxygenase-1 induction reverses the actions of interleukin-1β on hypoxia-inducible transcription factors and human chondrocyte metabolism in hypoxia.The CO-releasing molecule CORM-2 is a novel regulator of the inflammatory process in osteoarthritic chondrocytes.Taking a HIF pill for old age diseases?
P2860
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P2860
Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Hypoxia-inducible factor 1alph ...... e 1 in articular chondrocytes.
@en
Hypoxia-inducible factor 1alph ...... e 1 in articular chondrocytes.
@nl
type
label
Hypoxia-inducible factor 1alph ...... e 1 in articular chondrocytes.
@en
Hypoxia-inducible factor 1alph ...... e 1 in articular chondrocytes.
@nl
prefLabel
Hypoxia-inducible factor 1alph ...... e 1 in articular chondrocytes.
@en
Hypoxia-inducible factor 1alph ...... e 1 in articular chondrocytes.
@nl
P2093
P2860
P921
P356
P1476
Hypoxia-inducible factor 1alph ...... e 1 in articular chondrocytes.
@en
P2093
F F Hennig
P2860
P304
P356
10.1002/ART.23136
P577
2007-12-01T00:00:00Z