Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells.
about
Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of NanogKank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signalingThe Rho-Rock-Myosin signaling axis determines cell-cell integrity of self-renewing pluripotent stem cellsShort-term serum-free culture reveals that inhibition of Gsk3β induces the tumor-like growth of mouse embryonic stem cellsLeukemia inhibitory factor (LIF)Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotencyDistinct effects of EGFR ligands on human mammary epithelial cell differentiationThe Grb2/Mek pathway represses Nanog in murine embryonic stem cellsPhosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted lociForced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expressionAkt3 is responsible for the survival and proliferation of embryonic stem cellsDissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling.Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivativesCB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signalingPRDM Proteins: Molecular Mechanisms in Signal Transduction and Transcriptional Regulation.Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratumImpact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice.A Hyper-Crosslinked Carbohydrate Polymer Scaffold Facilitates Lineage Commitment and Maintains a Reserve Pool of Proliferating Cardiovascular Progenitors.FOXO1 is an essential regulator of pluripotency in human embryonic stem cells.A genome-wide siRNA screen identifies novel phospho-enzymes affecting Wnt/β-catenin signaling in mouse embryonic stem cells.The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming.Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells.LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers.Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state.CC chemokine ligand 2 and leukemia inhibitory factor cooperatively promote pluripotency in mouse induced pluripotent cells.Retinoic acid regulates Kit translation during spermatogonial differentiation in the mouseLarge scale phosphoproteome profiles comprehensive features of mouse embryonic stem cells.Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesisSox2 expression is regulated by a negative feedback loop in embryonic stem cells that involves AKT signaling and FoxO1.Akt increases sox2 expression in adult hippocampal neural progenitor cells, but increased sox2 does not promote proliferation.Ketamine affects the neurogenesis of rat fetal neural stem progenitor cells via the PI3K/Akt-p27 signaling pathwayZscan4 is regulated by PI3-kinase and DNA-damaging agents and directly interacts with the transcriptional repressors LSD1 and CtBP2 in mouse embryonic stem cellsNeural differentiation from embryonic stem cells in vitro: An overview of the signaling pathways.The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro.Epigenetic modifications and self-renewal regulation of mouse germline stem cellsAkt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells.Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation.How are pluripotent cells captured in culture?
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P2860
Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Activation of Akt signaling is ...... primate embryonic stem cells.
@en
Activation of Akt signaling is ...... primate embryonic stem cells.
@nl
type
label
Activation of Akt signaling is ...... primate embryonic stem cells.
@en
Activation of Akt signaling is ...... primate embryonic stem cells.
@nl
prefLabel
Activation of Akt signaling is ...... primate embryonic stem cells.
@en
Activation of Akt signaling is ...... primate embryonic stem cells.
@nl
P2093
P356
P1433
P1476
Activation of Akt signaling is ...... primate embryonic stem cells.
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1209307
P407
P50
P577
2006-05-01T00:00:00Z