Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

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TRAP1: a viable therapeutic target for future cancer treatments?Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain.Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer

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P2860

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

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http://www.wikidata.org/entity/Q46939691

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-hans

2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

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Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

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Item

label

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

@en

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

@nl

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Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

@en

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

@nl

P1476

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads

@en

P2093

Andrea Rasola

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David A Agard

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Elisabetta Moroni

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Ilda D'Annessa

http://www.w3.org/2001/XMLSchema#string

Jiahui Tao

http://www.w3.org/2001/XMLSchema#string

Marzia Pennati

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P2860

The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase

Corresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulations

Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1

Targeting the dynamic HSP90 complex in cancer

Stressing the development of small molecules targeting HSP90

Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

HSP90 and the chaperoning of cancer

Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.

Hsp90 molecular chaperone inhibitors: are we there yet?

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5188-5192

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scholarly article

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10.1002/CHEM.201700169

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English

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2017-03-22T00:00:00Z

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28207175

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5927549

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Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

about

P2860

P2860

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932