An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.
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Bis-arylidene oxindoles as anti-breast-cancer agents acting via the estrogen receptor.Schiff bases of indoline-2,3-dione (isatin) with potential antiproliferative activity.Methyl 2-acetamido-2-(1-acetyl-3-hydr-oxy-2-oxoindolin-3-yl)propanoate.5-Chloro-1-(4-meth-oxy-benz-yl)indoline-2,3-dione.[18F]- and [11C]-labeled N-benzyl-isatin sulfonamide analogues as PET tracers for apoptosis: synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98.Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists.Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo.Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathwayMarine compounds selectively induce apoptosis in female reproductive cancer cells but not in primary-derived human reproductive granulosa cellsN-alkylated isatins evade P-gp mediated efflux and retain potency in MDR cancer cell linesPurified brominated indole derivatives from Dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines.Use of ionic liquids as neoteric solvents in the synthesis of fused heterocycles.N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages.Simultaneous Assessment of the Efficacy and Toxicity of Marine Mollusc-Derived Brominated Indoles in an In Vivo Model for Early Stage Colon Cancer.An in vitro high-throughput assay for screening reproductive and toxic effects of anticancer compounds.Synthesis and anticancer activity of isatin-based pyrazolines and thiazolidines conjugates.{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic acid methyl ester (MIAM): its anti-cancer efficacy and intercalation mechanism identified via multi-model systems.Synthesis and in vitro evaluation of N-alkyl-3-hydroxy-3-(2-imino-3-methyl-5-oxoimidazolidin-4-yl)indolin-2-one analogs as potential anticancer agents.1-[(2-Chloro-3-quinol-yl)meth-yl]indoline-2,3-dione.An efficient and green reaction of isatins, 3-amino-1-phenyl-2-pyrazolin-5-one (3-amine-1H-pyrazole), and β-diketone in aqueous medium.Synthesis and anti-inflammatory activity evaluation of novel triazolyl-isatin hybrids.Allyl-isatin suppresses cell viability, induces cell cycle arrest, and promotes cell apoptosis in hepatocellular carcinoma HepG2 cells.Synthesis and carbonic anhydrase inhibitory properties of new spiroindoline-substituted sulphonamide compounds.Regioselective Suzuki–Miyaura reactions of 4,7-dichloro-N-methylisatin. Synthesis, anti-HIV activity and modeling studyReaction ofN-alkylisatins with 4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiosemicarbazide
P2860
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P2860
An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
An investigation into the cyto ...... l N-alkyl-substituted isatins.
@en
An investigation into the cyto ...... l N-alkyl-substituted isatins.
@nl
type
label
An investigation into the cyto ...... l N-alkyl-substituted isatins.
@en
An investigation into the cyto ...... l N-alkyl-substituted isatins.
@nl
prefLabel
An investigation into the cyto ...... l N-alkyl-substituted isatins.
@en
An investigation into the cyto ...... l N-alkyl-substituted isatins.
@nl
P2093
P356
P1476
An investigation into the cyto ...... el N-alkyl-substituted isatins
@en
P2093
John B Bremner
Julie M Locke
Kara L Vine
P304
P356
10.1021/JM0704189
P407
P577
2007-09-21T00:00:00Z