Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
about
The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleusThe hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expressionPilt, a novel peripheral membrane protein at tight junctions in epithelial cellsThe Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs LostGuanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modulesThe mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherinThe MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formationERBIN associates with p0071, an armadillo protein, at cell-cell junctions of epithelial cellsHuman homolog of Drosophila tumor suppressor Scribble negatively regulates cell-cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cellshScrib interacts with ZO-2 at the cell-cell junctions of epithelial cellsScribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of AktRole of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31Densin-180, a synaptic protein, links to PSD-95 through its direct interaction with MAGUIN-1Regulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptorThe hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteinsInteraction proteome of human Hippo signaling: modular control of the co-activator YAP1Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coliThe tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteinsScrib regulates PAK activity during the cell migration processDirect binding of Lgl2 to LGN during mitosis and its requirement for normal cell divisionMCC, a new interacting protein for Scrib, is required for cell migration in epithelial cellsInvolvement of Lgl and Mahjong/VprBP in cell competitionThe global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligaseEpithelial cell polarity: a major gatekeeper against cancer?Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervixA focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical developmentPolarity Determinants in Dendritic Spine Development and PlasticityGenes Regulating Epithelial Polarity Are Critical Suppressors of Esophageal OncogenesisThe heavy chain has its day: regulation of myosin-II assemblyEmerging role of cell polarity proteins in breast cancer progression and metastasisCell division and the maintenance of epithelial orderPlanar cell polarity signaling pathway in congenital heart diseasesEpithelial homeostasisPar6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers.Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary glandMechanical cell competition kills cells via induction of lethal p53 levelsRab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectodermLgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermisPhosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
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P2860
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
@en
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
@nl
type
label
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
@en
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
@nl
prefLabel
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
@en
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
@nl
P2093
P1433
P1476
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
@en
P2093
P304
P356
10.1126/SCIENCE.289.5476.113
P407
P577
2000-07-01T00:00:00Z