Deletion of proteasomal subunit S5a/Rpn10/p54 causes lethality, multiple mitotic defects and overexpression of proteasomal genes in Drosophila melanogaster.
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Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysisUse of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging.The proto-oncogene Int6 is essential for neddylation of Cul1 and Cul3 in Drosophila.Different degree in proteasome malfunction has various effects on root growth possibly through preventing cell division and promoting autophagic vacuolizationDifferential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress.Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome.A genetic suppressor of two dominant temperature-sensitive lethal proteasome mutants of Drosophila melanogaster is itself a mutated proteasome subunit geneProteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans.Role of the deubiquitylating enzyme DmUsp5 in coupling ubiquitin equilibrium to development and apoptosis in Drosophila melanogaster.Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse developmentIn vivo relevance of substrate recognition function of major Arabidopsis ubiquitin receptors.Decoding ubiquitin for mitosis.Interference of the dominant negative helix-loop-helix protein ID1 with the proteasomal subunit S5A causes centrosomal abnormalities.The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.Identification and characterization of a Drosophila proteasome regulatory network.Detrimental effects of proteasome inhibition activity in Drosophila melanogaster: implication of ER stress, autophagy, and apoptosis.Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.Overexpression of Dsk2/dUbqln results in severe developmental defects and lethality in Drosophila melanogaster that can be rescued by overexpression of the p54/Rpn10/S5a proteasomal subunit.Loss of 26S proteasome function leads to increased cell size and decreased cell number in Arabidopsis shoot organs.Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the β-TrCP homologue slimb.
P2860
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P2860
Deletion of proteasomal subunit S5a/Rpn10/p54 causes lethality, multiple mitotic defects and overexpression of proteasomal genes in Drosophila melanogaster.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-my
2003年学术文章
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2003年學術文章
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name
Deletion of proteasomal subuni ...... es in Drosophila melanogaster.
@en
Deletion of proteasomal subuni ...... es in Drosophila melanogaster.
@nl
type
label
Deletion of proteasomal subuni ...... es in Drosophila melanogaster.
@en
Deletion of proteasomal subuni ...... es in Drosophila melanogaster.
@nl
prefLabel
Deletion of proteasomal subuni ...... es in Drosophila melanogaster.
@en
Deletion of proteasomal subuni ...... es in Drosophila melanogaster.
@nl
P2093
P921
P356
P1476
Deletion of proteasomal subuni ...... es in Drosophila melanogaster.
@en
P2093
Andor Udvardy
Erika Virágh
Eva Kurucz
István Andó
István Kiss
Lajos Haracska
Péter Deák
Tamás Szlanka
P304
P356
10.1242/JCS.00332
P407
P577
2003-03-01T00:00:00Z