Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis.

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Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis.

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2017 nî lūn-bûn

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Excess cholesterol inhibits gl ...... ynamics in insulin exocytosis.

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Excess cholesterol inhibits gl ...... ynamics in insulin exocytosis.

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Excess cholesterol inhibits gl ...... ynamics in insulin exocytosis.

@en

Excess cholesterol inhibits gl ...... ynamics in insulin exocytosis.

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Excess cholesterol inhibits gl ...... ynamics in insulin exocytosis.

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Excess cholesterol inhibits gl ...... ynamics in insulin exocytosis.

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P1476

Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis

@en

P2093

Derek K Toomre

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P2860

Direct dynamin-actin interactions regulate the actin cytoskeleton.

A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosis

Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes.

Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells

An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.

Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.

Cholesterol accumulation increases insulin granule size and impairs membrane trafficking.

Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion.

Sweeping model of dynamin activity. Visualization of coupling between exocytosis and endocytosis under an evanescent wave microscope with green fluorescent proteins.

P304

2950-2962

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P31

scholarly article

P356

10.1111/JCMM.13207

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P433

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P478

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P50

Jonathan Bogan

Mingming Hao

Yingke Xu

P577

2017-05-25T00:00:00Z

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P698

28544529

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P921

exocytosis

P932

5661106

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