Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer.

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Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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Rapid screening and characteri ...... le orbitrap mass spectrometer.

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Rapid screening and characteri ...... le orbitrap mass spectrometer.

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label

Rapid screening and characteri ...... le orbitrap mass spectrometer.

@en

Rapid screening and characteri ...... le orbitrap mass spectrometer.

@nl

prefLabel

Rapid screening and characteri ...... le orbitrap mass spectrometer.

@en

Rapid screening and characteri ...... le orbitrap mass spectrometer.

@nl

P1476

Rapid screening and characteri ...... le orbitrap mass spectrometer.

@en

P2093

Dan Rock

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Ji Ma

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Ying Fang

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Zhican Wang

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Unbiased high-throughput screening of reactive metabolites on the linear ion trap mass spectrometer using polarity switch and mass tag triggered data-dependent acquisition.

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Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.

Role of residue 87 in the activity and regioselectivity of clozapine metabolism by drug-metabolizing CYP102A1 M11H: application for structural characterization of clozapine GSH conjugates.

High-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.

Simultaneous screening of glutathione and cyanide adducts using precursor ion and neutral loss scans-dependent product ion spectral acquisition and data mining tools.

Detection of reactive metabolites using isotope-labeled glutathione trapping and simultaneous neutral loss and precursor ion scanning with ultra-high-pressure liquid chromatography triple quadruple mass spectrometry

P2888

s00216-017-0814-8

P31

scholarly article

P356

10.1007/S00216-017-0814-8

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P407

English

P577

2017-12-18T00:00:00Z

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P698

29256080

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