DNA damage checkpoint maintenance through sustained Chk1 activity.
about
Replication stress in early S phase generates apparent micronuclei and chromosome rearrangement in fission yeast.Importance of a C-terminal conserved region of Chk1 for checkpoint function.Ataxin-3 promotes genome integrity by stabilizing Chk1.Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1Brc1-dependent recovery from replication stress.Initiation of DNA damage responses through XPG-related nucleasesMCL-1 localizes to sites of DNA damage and regulates DNA damage responseAntagonism of Chk1 signaling in the G2 DNA damage checkpoint by dominant alleles of Cdr1Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints.Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 functionChk1 Activation Protects Rad9A from Degradation as Part of a Positive Feedback Loop during Checkpoint Signalling.The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.Candidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the checkpoint kinase CHK1Turning off the G2 DNA damage checkpoint.Regulation of Chk1 by its C-terminal domain.Cell cycle regulation by checkpoints.Regulation of chk1.Ensuring the faithful execution of cytokinesis in Schizosaccharomyces pombe.Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint.HMGA2 inhibits apoptosis through interaction with ATR-CHK1 signaling complex in human cancer cells.Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest.Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint.Carboxy-terminal phosphorylation sites in Cdc25 contribute to enforcement of the DNA damage and replication checkpoints in fission yeast.Fission yeast Rnf4 homologs are required for DNA repair.Deubiquitinating enzyme USP3 controls CHK1 chromatin association and activation.
P2860
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P2860
DNA damage checkpoint maintenance through sustained Chk1 activity.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
DNA damage checkpoint maintenance through sustained Chk1 activity.
@en
DNA damage checkpoint maintenance through sustained Chk1 activity.
@nl
type
label
DNA damage checkpoint maintenance through sustained Chk1 activity.
@en
DNA damage checkpoint maintenance through sustained Chk1 activity.
@nl
prefLabel
DNA damage checkpoint maintenance through sustained Chk1 activity.
@en
DNA damage checkpoint maintenance through sustained Chk1 activity.
@nl
P356
P1476
DNA damage checkpoint maintenance through sustained Chk1 activity
@en
P2093
Christine Latif
Matthew J O'Connell
P304
P356
10.1242/JCS.01204
P407
P577
2004-06-22T00:00:00Z