The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.

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The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.

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http://www.wikidata.org/entity/Q47309289

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

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2017年學術文章

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name

The Anthelmintic Drug Niclosam ...... sociated Protein Kinase PINK1.

@en

The Anthelmintic Drug Niclosam ...... sociated Protein Kinase PINK1.

@nl

type

Item

label

The Anthelmintic Drug Niclosam ...... sociated Protein Kinase PINK1.

@en

The Anthelmintic Drug Niclosam ...... sociated Protein Kinase PINK1.

@nl

prefLabel

The Anthelmintic Drug Niclosam ...... sociated Protein Kinase PINK1.

@en

The Anthelmintic Drug Niclosam ...... sociated Protein Kinase PINK1.

@nl

P1476

The Anthelmintic Drug Niclosam ...... sociated Protein Kinase PINK1.

@en

P2093

Ageo Miccoli

http://www.w3.org/2001/XMLSchema#string

Erica Barini

http://www.w3.org/2001/XMLSchema#string

Farhat Khanim

http://www.w3.org/2001/XMLSchema#string

Federico Tinarelli

http://www.w3.org/2001/XMLSchema#string

Hachemi Kadri

http://www.w3.org/2001/XMLSchema#string

Katie Mulholland

http://www.w3.org/2001/XMLSchema#string

Kerry Burness

http://www.w3.org/2001/XMLSchema#string

Kevin D Read

http://www.w3.org/2001/XMLSchema#string

Laste Stojanovski

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Miratul M K Muqit

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P2860

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

Ubiquitin is phosphorylated by PINK1 to activate parkin

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease

The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1.

P304

425-429

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P31

scholarly article

P356

10.1002/CBIC.201700500

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Youcef Mehellou

J J Blow

P577

2018-01-24T00:00:00Z

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P698

29226533

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P932

5901409

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