Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs.
about
Drug discovery beyond the rule of 5 - Opportunities and challenges.Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules.Molecular descriptors for polarity: the need of going beyond polar surface area.Oral Administration of Peptide-Based Drugs: Beyond Lipinski's Rule.Pyrazolo[1,5-a]pyrimidine-based macrocycles as novel HIV-1 inhibitors: a patent evaluation of WO2015123182.Concise Synthesis of Tetrazole MacrocycleStereochemistry Balances Cell Permeability and Solubility in the Naturally Derived Phepropeptin Cyclic Peptides.Progress towards the broad use of non-peptide synthetic macrocycles in drug discovery.Two-Step Synthesis of Complex Artificial Macrocyclic Compounds.Medium-Sized-Ring Analogues of Dibenzodiazepines by a Conformationally Induced Smiles Ring Expansion.Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings.Modulation of Oral Bioavailability and Metabolism for Closely Related Cyclic Hexapeptides.Lipophilicity prediction of peptides and peptide derivatives by consensus machine learningConformational Sampling of Macrocyclic Drugs in Different Environments: Can We Find the Relevant Conformations?
P2860
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P2860
Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh-hant
name
Quantifying the chameleonic pr ...... r high-molecular-weight drugs.
@en
Quantifying the chameleonic pr ...... r high-molecular-weight drugs.
@nl
type
label
Quantifying the chameleonic pr ...... r high-molecular-weight drugs.
@en
Quantifying the chameleonic pr ...... r high-molecular-weight drugs.
@nl
prefLabel
Quantifying the chameleonic pr ...... r high-molecular-weight drugs.
@en
Quantifying the chameleonic pr ...... r high-molecular-weight drugs.
@nl
P2093
P2860
P1433
P1476
Quantifying the chameleonic pr ...... r high-molecular-weight drugs.
@en
P2093
Adrian Whitty
David R Hall
Dmitri Beglov
Lauren Viarengo
Mengqi Zhong
P2860
P304
P356
10.1016/J.DRUDIS.2016.02.005
P50
P577
2016-02-15T00:00:00Z