Classification analysis of P-glycoprotein substrate specificity. - Wikidata - wikimedia - TriplyDB

Classification analysis of P-glycoprotein substrate specificity.

Classification analysis of P-glycoprotein substrate specificity.

http://www.wikidata.org/entity/Q47326688

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Killing them with kindness? In-hive medications may inhibit xenobiotic efflux transporters and endanger honey bees Overcoming cisplatin resistance by mTOR inhibitor in lung cancer.A multi-system approach assessing the interaction of anticonvulsants with P-gp Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography A dual-fluorescence high-throughput cell line system for probing multidrug resistance.Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid.Pluronics and MDR reversal: an update.In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin Optimization of the antitumor activity of sequence-specific pyrrolobenzodiazepine derivatives based on their affinity for ABC transporters.Impact of p-glycoprotein inhibition and lipopolysaccharide administration on blood-brain barrier transport of colistin in mice Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance Reproducibility of quantitative (R)-[11C]verapamil studies.Role of efflux pumps and metabolising enzymes in drug delivery.Blood-brain barrier P-glycoprotein function in healthy subjects and Alzheimer's disease patients: effect of polymorphisms in the ABCB1 gene.P-glycoprotein function at the blood-brain barrier: effects of age and gender.The road map to oral bioavailability: an industrial perspective.The rise of PAMPA.Predictive models for oral drug absorption: from in silico methods to integrated dynamical models.Modeling kinetics of subcellular disposition of chemicals.P-glycoprotein efflux transporter activity often displays biphasic dose-response relationships.P-glycoprotein deficient mouse in situ blood-brain barrier permeability and its prediction using an in combo PAMPA model.Effect of potential amine prodrugs of selective neuronal nitric oxide synthase inhibitors on blood-brain barrier penetration.The right compound in the right assay at the right time: an integrated discovery DMPK strategy.The significance of acid/base properties in drug discovery Improving the prediction of drug disposition in the brain.In vitro prediction of brain penetration - a case for free thinking?Strategies to assess blood-brain barrier penetration.Methodologies to assess drug permeation through the blood-brain barrier for pharmaceutical research.Therapeutic potential of nanocarrier for overcoming to P-glycoprotein.Implicating ABC Transporters in Insecticide Resistance: Research Strategies and a Decision Framework.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.The forgotten or underestimated relevance of biopharmaceutical-based assessments for the oral absorption studies of oxime reactivators.Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design.Synthesis and evaluation of new radioligands [(11)C]A-833834 and [(11)C]A-752274 for positron-emission tomography of α7-nicotinic acetylcholine receptors.The Use of Rule-Based and QSPR Approaches in ADME Profiling: A Case Study on Caco-2 Permeability.Use of shape similarities for the classification of P-glycoprotein substrates and nonsubstrates.Discovery DMPK: changing paradigms in the eighties, nineties and noughties.Discovery of anthranilamides as a novel class of inhibitors of neurotropic alphavirus replication.In silico model for P-glycoprotein substrate prediction: insights from molecular dynamics and in vitro studies.In-vitro evaluation of the P-glycoprotein interactions of a series of potentially CNS-active Amaryllidaceae alkaloids.

P2860

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P2860

Classification analysis of P-glycoprotein substrate specificity.

http://www.wikidata.org/entity/Q47326688

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

@zh-hant

name

Classification analysis of P-glycoprotein substrate specificity.

@en

Classification analysis of P-glycoprotein substrate specificity.

@nl

type

label

Classification analysis of P-glycoprotein substrate specificity.

@en

Classification analysis of P-glycoprotein substrate specificity.

@nl

prefLabel

Classification analysis of P-glycoprotein substrate specificity.

@en

Classification analysis of P-glycoprotein substrate specificity.

@nl

P1433

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Journal of Drug Targeting

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Classification analysis of P-glycoprotein substrate specificity.

@en

P2093

Alanas Petrauskas

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Alex Avdeef

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Pranas Japertas

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Remigijus Didziapetris

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P2860

Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump

Multidrug resistance in cancer: role of ATP-dependent transporters

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein.

Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure-activity relationship (QSAR) with the Abraham descriptors.

Prediction of polar surface area and drug transport processes using simple parameters and PLS statistics.

Classification of multidrug-resistance reversal agents using structure-based descriptors and linear discriminant analysis.

Evaluation of a vincristine resistant Caco-2 cell line for use in a calcein AM extrusion screening assay for P-glycoprotein interaction.

Transport of new non-cross-resistant antitumor compounds of the benzoperimidine family in multidrug resistant cells.

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7

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15203928

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