Construction and characterization of a recombinant plasminogen activator composed of an anti-fibrin single-chain antibody and low-molecular-weight urokinase.
about
Human complement receptor type 1-directed loading of tissue plasminogen activator on circulating erythrocytes for prophylactic fibrinolysisEndogenously generated plasmin at the vascular wall injury site amplifies lysine binding site-dependent plasminogen accumulation in microthrombi.Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature.Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculatureDelayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?Engineering of plasminogen activators for targeting to thrombus and heightening thrombolytic efficacy.Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single-Chain Antibody Specific for Activated GPIIb/IIIa.
P2860
Q30444430-B3A7DD76-6EF9-4903-B222-E1F4706E589FQ35586122-C11A788E-AE1E-4263-84E5-AE7B15DC7168Q35848131-D6901F97-FDAA-4247-A72A-E46780C38780Q36445835-943E5823-5EF7-48DD-85E6-7CE1FF6C6CB5Q36779378-71C3AAF9-06C6-4000-B354-3E2B188B320DQ38527633-AA6939AE-BCA1-4E22-BFB9-E55B8A830FBCQ41102431-9CDAFEEB-BA44-4FB9-9CD2-F1198BD0E024
P2860
Construction and characterization of a recombinant plasminogen activator composed of an anti-fibrin single-chain antibody and low-molecular-weight urokinase.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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2004年學術文章
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name
Construction and characterizat ...... ow-molecular-weight urokinase.
@en
Construction and characterizat ...... ow-molecular-weight urokinase.
@nl
type
label
Construction and characterizat ...... ow-molecular-weight urokinase.
@en
Construction and characterizat ...... ow-molecular-weight urokinase.
@nl
prefLabel
Construction and characterizat ...... ow-molecular-weight urokinase.
@en
Construction and characterizat ...... ow-molecular-weight urokinase.
@nl
P2093
P2860
P1476
Construction and characterizat ...... ow-molecular-weight urokinase.
@en
P2093
P2860
P304
P356
10.1111/J.1538-7836.2004.00697.X
P577
2004-05-01T00:00:00Z