ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export.
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Linking hnRNP Function to ALS and FTD Pathology.Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization.RNA-Binding Proteins in Amyotrophic Lateral Sclerosis
P2860
ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export.
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2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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ALS Associated Mutations in Ma ...... nd Impede mRNA Nuclear Export.
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ALS Associated Mutations in Ma ...... nd Impede mRNA Nuclear Export.
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type
label
ALS Associated Mutations in Ma ...... nd Impede mRNA Nuclear Export.
@en
ALS Associated Mutations in Ma ...... nd Impede mRNA Nuclear Export.
@nl
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ALS Associated Mutations in Ma ...... nd Impede mRNA Nuclear Export.
@en
ALS Associated Mutations in Ma ...... nd Impede mRNA Nuclear Export.
@nl
P2093
P2860
P1433
P1476
ALS Associated Mutations in Ma ...... and Impede mRNA Nuclear Export
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P2093
Ashley Boehringer
Gurkaran Singh
Krystine Garcia-Mansfield
Nadine Bakkar
Patrick Pirrotte
P2860
P2888
P356
10.1038/S41598-017-14924-6
P407
P577
2017-11-06T00:00:00Z