Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening.
about
Biosynthesis and functions of mycothiol, the unique protective thiol of ActinobacteriaThe Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic TargetsA neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferaseInhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics.Challenges of antibacterial discoverySelective small molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG).A glycosyltransferase inhibitor from a molecular fragment library simultaneously interferes with metal ion and substrate binding.Rhodanine as a scaffold in drug discovery: a critical review of its biological activities and mechanisms of target modulation.Drug targets in mycobacterial sulfur metabolism.New targets and inhibitors of mycobacterial sulfur metabolism.A small molecule that inhibits OGT activity in cells.Lipid intermediates in the biosynthesis of bacterial peptidoglycanTranscreener: screening enzymes involved in covalent regulation.Synthesis of New N,N'-Bis(5-arylidene-4-oxo-4,5-dihydrothiazolin-2-yl)piperazine Derivatives Under Microwave Irradiation and Preliminary Biological Evaluation.Non-carbohydrate inhibitors of the lectin DC-SIGN.The biosynthesis of peptidoglycan lipid-linked intermediates.First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness.Specific labeling of peptidoglycan precursors as a tool for bacterial cell wall studies.Peptidoglycan biosynthesis machinery: a rich source of drug targets.Viable screening targets related to the bacterial cell wall.Crystal structure of (E)-3-allyl-2-sulfanyl-idene-5-[(thio-phen-2-yl)methyl-idene]thia-zolidin-4-oneDiscovery of novel inhibitors of Mycobacterium tuberculosis MurG: homology modelling, structure based pharmacophore, molecular docking, and molecular dynamics simulations.Cloning of a cholesterol-alpha-glucosyltransferase from Helicobacter pylori.
P2860
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P2860
Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening.
description
2004 nî lūn-bûn
@nan
2004年の論文
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2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
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2004年學術文章
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name
Identification of selective in ...... via high-throughput screening.
@en
Identification of selective in ...... via high-throughput screening.
@nl
type
label
Identification of selective in ...... via high-throughput screening.
@en
Identification of selective in ...... via high-throughput screening.
@nl
prefLabel
Identification of selective in ...... via high-throughput screening.
@en
Identification of selective in ...... via high-throughput screening.
@nl
P2093
P1476
Identification of selective in ...... via high-throughput screening.
@en
P2093
Benjamin Gross
Brian Kraybill
Cindy Ginsberg
Jeremiah S Helm
Kittichoat Tiyanont
Suzanne Walker
P304
P356
10.1016/J.CHEMBIOL.2004.02.024
P577
2004-05-01T00:00:00Z