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Conus venom peptide pharmacologyδ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snailsChemical synthesis and structure of the prokineticin Bv8Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venomIdentification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriensThe Walker 256 Breast Cancer Cell- Induced Bone Pain Model in RatsThe Snake with the Scorpion's Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus)The mu opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathwayRapid Extraction and Identification of Maitotoxin and Ciguatoxin-Like Toxins from Caribbean and Pacific Gambierdiscus Using a New Functional BioassayBayesian model predicts the response of axons to molecular gradients.Axon guidance by growth-rate modulation.Evolution of separate predation- and defence-evoked venoms in carnivorous cone snailsThe long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability statesPharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a.Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1.Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy.Optimization and In Vivo Profiling of a Refined Rat Model of Walker 256 Breast Cancer Cell-Induced Bone Pain Using Behavioral, Radiological, Histological, Immunohistochemical and Pharmacological MethodsCiguatoxins activate specific cold pain pathways to elicit burning pain from cooling.Pharmacological characterization of α-elapitoxin-Al2a from the venom of the Australian pygmy copperhead (Austrelaps labialis): an atypical long-chain α-neurotoxin with only weak affinity for α7 nicotinic receptors.Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231ω-Conotoxin GVIA mimetics that bind and inhibit neuronal Ca(v)2.2 ion channels.Expression and pharmacology of endogenous Cav channels in SH-SY5Y human neuroblastoma cellsMultiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins.A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica.The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.Differential evolution and neofunctionalization of snake venom metalloprotease domainsRapid, opioid-sensitive mechanisms involved in transient receptor potential vanilloid 1 sensitization.Venom peptides as a rich source of cav2.2 channel blockers.Development of a μO-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathwaysVenomics: a new paradigm for natural products-based drug discovery.Natural product ligands of TRP channels.Development and optimization of FLIPR high throughput calcium assays for ion channels and GPCRs.Therapeutic potential of cone snail venom peptides (conopeptides).No gain, no pain: NaV1.7 as an analgesic target.Therapeutic opportunities for targeting cold pain pathways.Ciguatera fish poisoning: a first epidemic in Germany highlights an increasing risk for European countries.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Irina Vetter
@ast
Irina Vetter
@en
Irina Vetter
@es
Irina Vetter
@nl
Irina Vetter
@sl
type
label
Irina Vetter
@ast
Irina Vetter
@en
Irina Vetter
@es
Irina Vetter
@nl
Irina Vetter
@sl
prefLabel
Irina Vetter
@ast
Irina Vetter
@en
Irina Vetter
@es
Irina Vetter
@nl
Irina Vetter
@sl
P1053
A-6035-2010
P106
P2038
Irina_Vetter
P21
P31
P3829
P496
0000-0002-3594-9588