Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
about
Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.HDAC2/3 binding and deacetylation of BubR1 initiates spindle assembly checkpoint silencing.Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer.TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer.TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC
P2860
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年學術文章
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2017年學術文章
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name
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
@en
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
@nl
type
label
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
@en
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
@nl
prefLabel
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
@en
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
@nl
P2093
P2860
P1433
P1476
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit
@en
P2093
Christine Khoo
Daniel Henry Marks
Riddhi Shah
Robert Benezra
Yvette Chin
P2860
P304
P356
10.1016/J.CELREP.2017.05.021
P577
2017-05-01T00:00:00Z