CFTR potentiators: from bench to bedside.

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A common mechanism for CFTR potentiators.Structural mechanisms of CFTR function and dysfunction.

P2860

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CFTR potentiators: from bench to bedside.

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http://www.wikidata.org/entity/Q47599899

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2017 nî lūn-bûn

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2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

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2017年學術文章

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name

CFTR potentiators: from bench to bedside.

@en

CFTR potentiators: from bench to bedside.

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type

Item

label

CFTR potentiators: from bench to bedside.

@en

CFTR potentiators: from bench to bedside.

@nl

prefLabel

CFTR potentiators: from bench to bedside.

@en

CFTR potentiators: from bench to bedside.

@nl

P1476

CFTR potentiators: from bench to bedside.

@en

P2093

Kang-Yang Jih

http://www.w3.org/2001/XMLSchema#string

Tzyh-Chang Hwang

http://www.w3.org/2001/XMLSchema#string

Wen-Ying Lin

http://www.w3.org/2001/XMLSchema#string

Yoshiro Sohma

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P2860

Cystic Fibrosis: Lessons from the Sweat Gland

Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

The ABC protein turned chloride channel whose failure causes cystic fibrosis

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

Curcumin and genistein: the combined effects on disease-associated CFTR mutants and their clinical implications

Molecular pharmacology of the CFTR Cl- channel.

Potentiation of disease-associated cystic fibrosis transmembrane conductance regulator mutants by hydrolyzable ATP analogs.

Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner.

P304

98-104

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scholarly article

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10.1016/J.COPH.2017.09.015

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P478

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P577

2017-10-23T00:00:00Z

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29073476

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P932

5723237

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CFTR potentiators: from bench to bedside.

about

P2860

P2860

CFTR potentiators: from bench to bedside.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P577

P698

P932