Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells.
about
Transcriptional regulation by AIRE: molecular mechanisms of central toleranceThe role of the intestinal context in the generation of tolerance and inflammationRole of the intestinal cytokine microenvironment in shaping the intraepithelial lymphocyte repertoireHomotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentSkint-1 is a highly specific, unique selecting component for epidermal T cellsThe timing of TCR alpha expression critically influences T cell development and selectionLineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.Genomic definition of multiple ex vivo regulatory T cell subphenotypes.Alphabeta versus gammadelta lineage choice at the first TCR-controlled checkpointDirect recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function.αβT cell receptors expressed by CD4(-)CD8αβ(-) intraepithelial T cells drive their fate into a unique lineage with unusual MHC reactivities.Alternative memory in the CD8 T cell lineageElevated T cell receptor signaling identifies a thymic precursor to the TCRαβ(+)CD4(-)CD8β(-) intraepithelial lymphocyte lineage.Ly49E expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases.How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic isletsEvaluation of the immunoregulatory activity of intraepithelial lymphocytes in a mouse model of chronic intestinal inflammation.CCR10 is important for the development of skin-specific gammadeltaT cells by regulating their migration and locationSignaling in thymic selection.Transcription factor T-bet regulates intraepithelial lymphocyte functional maturation.Transcriptomes of the B and T lineages compared by multiplatform microarray profiling.Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.The light and dark sides of intestinal intraepithelial lymphocytesThe same genomic region conditions clonal deletion and clonal deviation to the CD8alphaalpha and regulatory T cell lineages in NOD versus C57BL/6 mice.Thymic negative selection is functional in NOD mice.Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletionProgrammed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cellsReproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cellsalpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles.In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues.Cross-presenting CD103+ dendritic cells are protected from influenza virus infection.Transcription factor networks directing the development, function, and evolution of innate lymphoid effectorsEstablishment and functioning of intrathymic microenvironments.Functional reprogramming of the primary immune response by T cell receptor antagonism.Characterization of the early stages of thymic NKT cell development.Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes.A shared gene-expression signature in innate-like lymphocytes.Selection of self-reactive T cells in the thymus.Development and selection of gammadelta T cells.Thymic differentiation of TCR alpha beta(+) CD8 alpha alpha(+) IELs.Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells
P2860
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P2860
Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Self-reactivity in thymic doub ...... istics of innate immune cells.
@en
Self-reactivity in thymic doub ...... istics of innate immune cells.
@nl
type
label
Self-reactivity in thymic doub ...... istics of innate immune cells.
@en
Self-reactivity in thymic doub ...... istics of innate immune cells.
@nl
prefLabel
Self-reactivity in thymic doub ...... istics of innate immune cells.
@en
Self-reactivity in thymic doub ...... istics of innate immune cells.
@nl
P2093
P2860
P356
P1433
P1476
Self-reactivity in thymic doub ...... istics of innate immune cells.
@en
P2093
Christophe Benoist
Diane Mathis
Tetsuya Yamagata
P2860
P304
P356
10.1038/NI1070
P407
P577
2004-05-09T00:00:00Z