Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
about
Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.Drug development: Allosteric inhibitors hit USP7 hard.Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis.Targeting HAUSP in both p53 wildtype and p53-mutant tumors.Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.Molecular dynamics simulation reveals the possible druggable of USP7Identification and Characterization of USP7 Targets in Cancer CellsUSP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemiaThe structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channelUSP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
P2860
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P2860
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
description
2017 nî lūn-bûn
@nan
2017年の論文
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2017年学术文章
@wuu
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
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2017年學術文章
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name
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
@en
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
@nl
type
label
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
@en
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
@nl
prefLabel
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
@en
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
@nl
P2093
P2860
P50
P356
P1433
P1476
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
@en
P2093
Adam C Talbot
Adan Pinto-Fernandez
Agnes C L Martin
Alexandre J Buckmelter
Andrew P Turnbull
Angela V Toms
Bruce C Follows
C Gary Marshall
Christopher J Dinsmore
Claire Heride
P2860
P2888
P304
P356
10.1038/NATURE24451
P407
P577
2017-10-18T00:00:00Z