Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase
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The Ubiquitination of NF-κB Subunits in the Control of TranscriptionThe business of deubiquitination - location, location, locationDeubiquitinating enzymes in cellular signaling and disease regulationDeubiquitinating enzymes as oncotargetsA Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and ActivityA Role for USP7 in DNA ReplicationA 2.2 Å resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin bindingStructure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like DomainsInsights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and ProductA conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzymeUncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.The Ubp15 deubiquitinase promotes timely entry into S phase in Saccharomyces cerevisiaeDeubiquitinases: Novel Therapeutic Targets in Immune Surveillance?Undercover: gene control by metabolites and metabolic enzymesModulation of the p53/MDM2 interplay by HAUSP inhibitorsAllosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20The role of UBL domains in ubiquitin-specific proteasesCrystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental DisorderUbiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC protein and preventing XPC protein from undergoing ultraviolet light-induced and VCP/p97 protein-regulated proteolysis.Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes.Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis.Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7.A ubiquitin-specific protease possesses a decisive role for adenovirus replication and oncogene-mediated transformation.Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN.Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.Rapid optimization of labeled ubiquitinated peptides for monitoring deubiquitinases activities.USP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168.Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.Using protein motion to read, write, and erase ubiquitin signals.Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.Spatiotemporal regulation of the ubiquitinated cargo-binding activity of Rabex-5 in the endocytic pathway.Ubiquitin-specific protease 7 expression is a prognostic factor in epithelial ovarian cancer and correlates with lymph node metastasis.Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.Serine phosphorylation is critical for the activation of ubiquitin-specific protease 1 and its interaction with WD40-repeat protein UAF1.Transient kinetic analysis of USP2-catalyzed deubiquitination reveals a conformational rearrangement in the K48-linked diubiquitin substrateUSP7 and Daxx regulate mitosis progression and taxane sensitivity by affecting stability of Aurora-A kinaseExpression of HAUSP in gliomas correlates with disease progression and survival of patientsSubstrate activation and conformational dynamics of guanosine 5'-monophosphate synthetase.HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.
P2860
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P2860
Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@ast
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@en
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@nl
type
label
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@ast
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@en
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@nl
prefLabel
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@ast
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@en
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@nl
P2093
P50
P3181
P1433
P1476
Mechanism of USP7/HAUSP activa ...... c regulation by GMP-synthetase
@en
P2093
Alex C Faesen
Anitha Shanmugham
Annette M G Dirac
P304
P3181
P356
10.1016/J.MOLCEL.2011.06.034
P577
2011-10-07T00:00:00Z