BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

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BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

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BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

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BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

@en

BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

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BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

@en

BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

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P1476

BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

@en

P2093

Hana Paculová

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Jiří Kohoutek

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Juraj Kramara

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Kamil Paruch

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Karel Souček

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Marek Svoboda

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Martin Mistrík

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Ondřej Hylse

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Radek Fedr

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Šárka Šimečková

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P2860

Hallmarks of Cancer: The Next Generation

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage

Comprehensive molecular portraits of human breast tumours

BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution

Successes and Challenges of PARP Inhibitors in Cancer Therapy

Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: a template-based approach--part 2

Structural and Functional Analysis of the Cdk13/Cyclin K Complex

P304

1010428317727479

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P31

scholarly article

P356

10.1177/1010428317727479

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P577

2017-10-01T00:00:00Z

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P698

29025359

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