Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
about
From dynamic expression patterns to boundary formation in the presomitic mesodermOscillatory regulation of Hes1: Discrete stochastic delay modelling and simulationNumber of active transcription factor binding sites is essential for the Hes7 oscillator.Timing by rhythms: Daily clocks and developmental rulersA proposed mechanism for the interaction of the segmentation clock and the determination front in somitogenesisFast synchronization of ultradian oscillators controlled by delta-notch signaling with cis-inhibition.Somitogenesis clock-wave initiation requires differential decay and multiple binding sites for clock proteinA spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamicsLessons from mathematically modeling the NF-κB pathway.Delta-Notch signalling in segmentationDelay-induced transient increase and heterogeneity in gene expression in negatively auto-regulated gene circuitsComputational models of the Notch network elucidate mechanisms of context-dependent signalingTopology and dynamics of the zebrafish segmentation clock core circuitThermodynamic state ensemble models of cis-regulationChemical memory reactions induced bursting dynamics in gene expressionInstability of Hes7 protein is crucial for the somite segmentation clockThe pharmacodynamics of the p53-Mdm2 targeting drug Nutlin: the role of gene-switching noiseReal-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells.Oscillations and variability in the p53 systemTABASCO: A single molecule, base-pair resolved gene expression simulator.Delayed coupling theory of vertebrate segmentation.Fourier analysis and systems identification of the p53 feedback loopSpatial stochastic modelling of the Hes1 gene regulatory network: intrinsic noise can explain heterogeneity in embryonic stem cell differentiation.Spatial gradients of protein-level time delays set the pace of the traveling segmentation clock waves.Strengths and limitations of period estimation methods for circadian data.Elucidating the digital control mechanism for DNA damage repair with the p53-Mdm2 system: single cell data analysis and ensemble modelling.Setting the tempo in development: an investigation of the zebrafish somite clock mechanismExtended analyses of the Wnt/beta-catenin pathway: robustness and oscillatory behaviour.Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamicsGeneralized binomial tau-leap method for biochemical kinetics incorporating both delay and intrinsic noise.Bifurcation analysis informs Bayesian inference in the Hes1 feedback loopModeling the role of p53 pulses in DNA damage- induced cell death decision.Dynamic telomerase gene suppression via network effects of GSK3 inhibitionPredicted functions of MdmX in fine-tuning the response of p53 to DNA damage.Probability distributed time delays: integrating spatial effects into temporal models.DREAM3: network inference using dynamic context likelihood of relatedness and the inferelatorThe origins of time-delay in template biopolymerization processes.Simulation methods with extended stability for stiff biochemical Kinetics.Intron delays and transcriptional timing during development.Modeling delay in genetic networks: from delay birth-death processes to delay stochastic differential equations.
P2860
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P2860
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
@en
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
@nl
type
label
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
@en
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
@nl
prefLabel
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
@en
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
@nl
P1433
P1476
Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.
@en
P2093
Nicholas A M Monk
P304
P356
10.1016/S0960-9822(03)00494-9
P407
P577
2003-08-01T00:00:00Z