Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.
about
Defining a new biomarker for the autoimmune component of Multiple Sclerosis: Th40 cells.CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunityT-cell receptor revision: friend or foe?Pro-inflammatory T-lymphocytes rapidly infiltrate into the brain and contribute to neuronal injury following cardiac arrest and cardiopulmonary resuscitationA CD40-targeted peptide controls and reverses type 1 diabetes in NOD mice.Galectin-9 controls CD40 signaling through a Tim-3 independent mechanism and redirects the cytokine profile of pathogenic T cells in autoimmunity.Antigen-Experienced CD4lo T Cells Are Linked to Deficient Contraction of the Immune Response in Autoimmune DiabetesTh40 cells (CD4+CD40+ Tcells) drive a more severe form of Experimental Autoimmune Encephalomyelitis than conventional CD4 T cells.High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunityDisruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes.An alternative role for Foxp3 as an effector T cell regulator controlled through CD40CD40 interacts directly with RAG1 and RAG2 in autoaggressive T cells and Fas prevents CD40-induced RAG expression.CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes.CD40/CD40 ligand interactions in immune responses and pulmonary immunity.Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse.High Risk First Degree Relatives of Type 1 Diabetics: An Association with Increases in CXCR3(+) T Memory Cells Reflecting an Enhanced Activity of Th1 Autoimmune Response.Of the multiple mechanisms leading to type 1 diabetes, T cell receptor revision may play a prominent role (is type 1 diabetes more than a single disease?).Overlooked Mechanisms in Type 1 Diabetes Etiology: How Unique Costimulatory Molecules Contribute to DiabetogenesisCD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes.The antidiabetic effect of mesenchymal stem cells is unrelated to their transdifferentiation potential but to their capability to restore Th1/Th2 balance and to modify the pancreatic microenvironment.Role of CD40-dependent signal in induction of recombinase RAG-1 expression in peripheral T cells of patients with autoimmune diabetes mellitus.The Type 1 Diabetes PhysioLab Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse.Dosing and timing effects of anti-CD40L therapy: predictions from a mathematical model of type 1 diabetes.CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance
P2860
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P2860
Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Peripheral CD4loCD40+ auto-agg ...... n-dependent diabetes mellitus.
@en
Peripheral CD4loCD40+ auto-agg ...... n-dependent diabetes mellitus.
@nl
type
label
Peripheral CD4loCD40+ auto-agg ...... n-dependent diabetes mellitus.
@en
Peripheral CD4loCD40+ auto-agg ...... n-dependent diabetes mellitus.
@nl
prefLabel
Peripheral CD4loCD40+ auto-agg ...... n-dependent diabetes mellitus.
@en
Peripheral CD4loCD40+ auto-agg ...... n-dependent diabetes mellitus.
@nl
P356
P1476
Peripheral CD4loCD40+ auto-agg ...... in-dependent diabetes mellitus
@en
P2093
Dan M Waid
David H Wagner
P304
P356
10.1002/EJI.200324703
P407
P577
2004-05-01T00:00:00Z