Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma.

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The impact of cancer-associated fibroblasts on major hallmarks of pancreatic cancer

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Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma.

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http://www.wikidata.org/entity/Q47696181

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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Fibroblast activation protein ...... creatic ductal adenocarcinoma.

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Fibroblast activation protein ...... creatic ductal adenocarcinoma.

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Item

label

Fibroblast activation protein ...... creatic ductal adenocarcinoma.

@en

Fibroblast activation protein ...... creatic ductal adenocarcinoma.

@nl

prefLabel

Fibroblast activation protein ...... creatic ductal adenocarcinoma.

@en

Fibroblast activation protein ...... creatic ductal adenocarcinoma.

@nl

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Fibroblast activation protein ...... creatic ductal adenocarcinoma.

@en

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Chung-Pin Li

http://www.w3.org/2001/XMLSchema#string

Diana Avery

http://www.w3.org/2001/XMLSchema#string

Elizabeth L Buza

http://www.w3.org/2001/XMLSchema#string

James Monslow

http://www.w3.org/2001/XMLSchema#string

Priya Govindaraju

http://www.w3.org/2001/XMLSchema#string

P2860

Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts

Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α

Genetics and biology of pancreatic ductal adenocarcinoma

FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor

EMT and dissemination precede pancreatic tumor formation

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells.

Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity.

Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma.

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

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scholarly article

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10.1172/JCI.INSIGHT.92232

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2017-10-05T00:00:00Z

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28978805

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5841864

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Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma.

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P2860

P2860

Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma.

description

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type

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P1433

P1476

P2093

P2860

P31

P356

P433

P478

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P932

P356

P1433

P1476

P2093

P2860

P31

P356

P433

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P50

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P698

P932