about
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxisMechanism for down-regulation of CD28 by Nef.CHD7 cooperates with PBAF to control multipotent neural crest formationZika Virus Infection Induces Cranial Neural Crest Cells to Produce Cytokines at Levels Detrimental for NeurogenesisSignaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell developmentA PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodellingJarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cellsETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formationSequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates.Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis.Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.T-cell receptor:CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques.Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis.Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells.H3K27 demethylases, at long last.Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crestChromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cellsCo-transcriptional R-loops are the main cause of estrogen-induced DNA damage.Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus.A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancerEnhancer divergence and cis-regulatory evolution in the human and chimp neural crest.Disrupting surfaces of nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo.The human immunodeficiency virus type 1 nef gene can to a large extent replace simian immunodeficiency virus nef in vivo.Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques.Disrupting Surfaces of Nef Required for Downregulation of CD4 and for Enhancement of Virion Infectivity Attenuates Simian Immunodeficiency Virus Replication In Vivo.Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators.Fallen immortals.Transcription-coupled changes in nuclear mobility of mammalian cis-regulatory elements.Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.PDTM-29. TRANSCRIPTIONAL DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMATranscription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage ResponsesFaculty of 1000 evaluation for Genome-wide reprogramming in the mouse germ line entails the base excision repair pathwayContribution of human embryonic stem cells to mouse blastocystsSystematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulationZscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage
P50
Q21146434-5A7DD52A-92FF-4D21-AE9C-1239053BCCDAQ24291079-79E736EB-329B-4B3B-97D4-246FC2088C91Q24630725-6EED6012-EF19-46C7-BDE4-4BFDA2620376Q27094488-35E42F63-9E06-4C72-8C5C-3AC38E24B2B9Q28186461-18E16C1C-8092-4364-BA0F-56973A1FAF9DQ28242453-D9486237-4839-454C-8CCB-9DE0C3312ECFQ28585926-DB6651A2-7990-4D7B-AB97-01C2EC9CD110Q28589379-E8C2C009-FE9E-4770-BA40-64D4473C7E6FQ30176410-14B9E259-E453-43C7-BCAE-7B4C9BB7AB6CQ33890912-CDEAF5C6-7F43-4716-A884-FE994CFCB181Q33902815-C32C7910-4464-4289-A169-DEE8CB3DC408Q33911849-BCC831B5-F8E5-43AE-8B23-A528080CDDE2Q34359050-73C64C80-47FD-4EFF-9F8E-A1C28C1542BBQ34556377-D7800DC7-3315-4F58-B138-0216989511C3Q35105271-415E2BB2-6513-4ACD-93BB-AFB9B877754CQ36049159-6E3E3857-C6A9-435D-BF8D-36DAA951A52EQ36965110-43A7DC2C-7DE6-47D9-9420-F61BA70BA98BQ37115627-B03402AE-AC91-4D51-8C11-E11CE1C13CDBQ37238475-640122E7-5B21-4D4C-BC4B-2186DA0C0984Q37270352-D88BE724-13BE-4625-A5EA-206289A52DA1Q37596524-F2B65DC4-A52D-44CD-B07B-63AE2CDDF522Q37739218-F2BB4E94-BAFD-428A-A989-CA27C29F297AQ38964475-8E59B3F3-C234-47C4-9A3B-610AD0F5C58BQ39539413-D80C0AD9-78C6-4FF1-ACDA-028502E2F755Q39595906-88F315C6-9A88-4410-A19F-AC6236F57209Q40293015-BF66A956-58E2-4DA3-9E54-2E489041944FQ46700735-9C14F7EF-27D3-40DE-8053-F734FCCD55AAQ46985603-8D354A32-A950-46E3-B81D-6F032F566596Q47277173-086673AC-0507-4335-BB08-B2ACFB7C2C70Q47979703-690661FB-E2C5-4BA1-8E5F-249C42B1CA54Q48163556-D0C1B45E-1CC6-4F3C-91DB-C5D8EA6149ABQ49821255-00C4B0E2-AE02-4C7E-8233-5067834EC408Q56770569-A4B838C7-CD03-49DE-BB27-FDCDD2FD8B45Q56770572-4CBAE730-81B6-4765-9A8B-85E98999573CQ56770589-7A848341-22E6-4AF7-ADF4-1F3EE348B895Q56770599-9E67866C-CB79-4DD0-BCBE-E384F8687440Q58802640-10DCDDD4-4B18-4C91-98BF-CC662BAAA576Q90700524-013F6FF4-EBB2-40EC-B16E-638F340ECE46
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Tomek Swigut
@ast
Tomek Swigut
@en
Tomek Swigut
@es
Tomek Swigut
@nl
Tomek Swigut
@sl
type
label
Tomek Swigut
@ast
Tomek Swigut
@en
Tomek Swigut
@es
Tomek Swigut
@nl
Tomek Swigut
@sl
prefLabel
Tomek Swigut
@ast
Tomek Swigut
@en
Tomek Swigut
@es
Tomek Swigut
@nl
Tomek Swigut
@sl
P106
P21
P31
P496
0000-0002-7649-6781