about
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetesA human type 1 diabetes susceptibility locus maps to chromosome 21q22.3No linkage of P187S polymorphism in NAD(P)H: quinone oxidoreductase (NQO1/DIA4) and type 1 diabetes in the Danish population. DIEGG and DSGD. Danish IDDM Epidemiology and Genetics Group and The Danish Study Group of Diabetes in ChildhoodGenetics of type 1 diabetes mellitusIdentification and characterization of secretagogin promoter activityGenetic risk factors for type 1 diabetesZinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3Inhibition of the nuclear factor-κB pathway prevents beta cell failure and diet induced diabetes in Psammomys obesusIntegrative analysis for finding genes and networks involved in diabetes and other complex diseasesIs mortalin a candidate gene for T1DM ?A human phenome-interactome network of protein complexes implicated in genetic disordersIdentification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene ExpressionNovel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes.Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.Confirmation of novel type 1 diabetes risk loci in families.Tests for genetic interactions in type 1 diabetes: linkage and stratification analyses of 4,422 affected sib-pairs.Genetics of type 1 diabetes: what's next?Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics ConsortiumCurrent status and the future for the genetics of type I diabetes.Overview of the Type I Diabetes Genetics Consortium.Results of the MHC fine mapping workshop.IDDM12 (CTLA4) on 2q33 and IDDM13 on 2q34 in genetic susceptibility to type 1 diabetes (insulin-dependent).Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic PatientsNovel analytical methods applied to type 1 diabetes genome-scan data.Mass spectrometry is only one piece of the puzzle in clinical proteomics.Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia.Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping dataEvaluation of IL12B as a candidate type I diabetes susceptibility gene using data from the Type I Diabetes Genetics Consortium.Plasma proteome analysis of patients with type 1 diabetes with diabetic nephropathyThe type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes.Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY).No association of the IRS1 and PAX4 genes with type I diabetes.25-Hydroxyvitamin D and Peripheral Immune Mediators: Results from Two Nationwide Danish Pediatric Cohorts.A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.Screening newborns for candidate biomarkers of type 1 diabetes.Onset of type 1 diabetes: a dynamical instability.Finding diabetic nephropathy biomarkers in the plasma peptidome by high-throughput magnetic bead processing and MALDI-TOF-MS analysis.Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes
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