about
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders.Transcriptional activation of lysosomal exocytosis promotes cellular clearance.Transcription factor EB (TFEB) is a new therapeutic target for Pompe diseaseGene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency.In-Silico Analysis and Implementation of a Multicellular Feedback Control Strategy in a Synthetic Bacterial Consortium.Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Fabio Annunziata
@ast
Fabio Annunziata
@en
Fabio Annunziata
@es
Fabio Annunziata
@nl
Fabio Annunziata
@sl
type
label
Fabio Annunziata
@ast
Fabio Annunziata
@en
Fabio Annunziata
@es
Fabio Annunziata
@nl
Fabio Annunziata
@sl
prefLabel
Fabio Annunziata
@ast
Fabio Annunziata
@en
Fabio Annunziata
@es
Fabio Annunziata
@nl
Fabio Annunziata
@sl
P1053
D-5074-2016
P106
P21
P31
P3829
P496
0000-0001-8598-5459