Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
about
Glucocerebrosidase is shaking up the synucleinopathiesAutophagy in lysosomal storage disordersThe cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunctionThe crucial impact of lysosomes in aging and longevityMoving towards effective therapeutic strategies for Neuronal Ceroid LipofuscinosisSanfilippo syndrome: causes, consequences, and treatmentsThe role of TRPMLs in endolysosomal trafficking and functionImpairment of homeostasis in lysosomal storage disordersPermeation, regulation and control of expression of TRP channels by trace metal ionsThe endolysosomal system in cell death and survivalThe lysosome: from waste bag to potential therapeutic targetLocalized AL amyloidosis: a suicidal neoplasm?Regulation of lysosomal ion homeostasis by channels and transportersTFEB at a glanceTranscriptional and epigenetic regulation of autophagy in agingBeyond indigestion: emerging roles for lysosome-based signaling in human diseaseBiphasic regulation of lysosomal exocytosis by oxidative stressReprogramming of lysosomal gene expression by interleukin-4 and Stat6A rapid and sensitive method for measuring N-acetylglucosaminidase activity in cultured cellsA lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEBMTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseasesLysosomal exocytosis and lipid storage disorders.Lysosomal adaptation: how the lysosome responds to external cuesTime course of pathogenic and adaptation mechanisms in cystinotic mouse kidneysNovel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasisThe phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activationSafety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders.Zn2+ efflux through lysosomal exocytosis prevents Zn2+-induced toxicity.Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesisPompe disease: from pathophysiology to therapy and back againInduction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelaeTrex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genesSignals from the lysosome: a control centre for cellular clearance and energy metabolism.Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EBLysosomal physiology.Lysosome: regulator of lipid degradation pathways.Oncogenic H-Ras up-regulates acid β-hexosaminidase by a mechanism dependent on the autophagy regulator TFEB
P2860
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P2860
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
@ast
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
@en
type
label
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
@ast
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
@en
prefLabel
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
@ast
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
@en
P2093
P2860
P50
P1433
P1476
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
@en
P2093
Alessandro Fraldi
Antonella Pignata
Carmine Spampanato
Claudia Puri
Gelsomina Mansueto
Jose A Martina
Marco Sardiello
Michela Palmieri
Roman Polishchuk
Rosa Puertollano
P2860
P304
P356
10.1016/J.DEVCEL.2011.07.016
P407
P577
2011-09-01T00:00:00Z