Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice.
about
Functional analysis of human mutations in homeodomain transcription factor PITX3Homozygous nonsense mutation in the FOXE3 gene as a cause of congenital primary aphakia in humansImmortalization of neuronal progenitors using SV40 large T antigen and differentiation towards dopaminergic neuronsHigh throughput sequencing approaches to mutation discovery in the mouseCell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotypePitx3 controls multiple aspects of lens developmentGenetic mouse models of parkinsonism: strengths and limitations.laminin alpha 1 gene is essential for normal lens development in zebrafish.Motor deficits and altered striatal gene expression in aphakia (ak) mice.Microphthalmia in Texel sheep is associated with a missense mutation in the paired-like homeodomain 3 (PITX3) gene.Activated Ras alters lens and corneal development through induction of distinct downstream targets.Genetic regulation of pituitary gland development in human and mouseThe role of transcription factor Pitx3 in dopamine neuron development and Parkinson's disease.MIP/Aquaporin 0 represents a direct transcriptional target of PITX3 in the developing lens.Mutational analysis of the RNX gene in congenital central hypoventilation syndrome.Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice.The role of the posterior ciliary body in the biosynthesis of vitreous humour.Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in micePitx3 is required for development of substantia nigra dopaminergic neurons.L-dopa reverses behavioral deficits in the Pitx3 mouse fetusAnterior eye development and ocular mesenchyme: new insights from mouse models and human diseasesMidbrain dopaminergic development in vivo and in vitro from embryonic stem cells.Pax6 is misexpressed in Sox1 null lens fiber cells.Prenatal ontogeny of the dopamine-dependent neurobehavioral phenotype in Pitx3-deficient mice.Molecular pathogenesis, experimental models and new therapeutic strategies for Parkinson's disease.Congenital corneal opacities - a surgical approach to nomenclature and classification.Dominant inhibition of lens placode formation in miceImpaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.Novel and recurrent PITX3 mutations in Belgian families with autosomal dominant congenital cataract and anterior segment dysgenesis have similar phenotypic and functional characteristics.Molecular and cellular aspects of amphibian lens regeneration.Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update.Functional Interplay between Dopaminergic and Serotonergic Neuronal Systems during Development and Adulthood.Conserved genetic pathways associated with microphthalmia, anophthalmia, and coloboma.A heterozygous c-Maf transactivation domain mutation causes congenital cataract and enhances target gene activation.Notch signaling regulates growth and differentiation in the mammalian lensDevelopmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome.Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survivalNeurobehavioral Anomalies in the Pitx3/ak Murine Model of Parkinson's Disease and MPTP.
P2860
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P2860
Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Deletion in the promoter regio ...... homeobox gene in aphakia mice.
@en
Deletion in the promoter regio ...... homeobox gene in aphakia mice.
@nl
type
label
Deletion in the promoter regio ...... homeobox gene in aphakia mice.
@en
Deletion in the promoter regio ...... homeobox gene in aphakia mice.
@nl
prefLabel
Deletion in the promoter regio ...... homeobox gene in aphakia mice.
@en
Deletion in the promoter regio ...... homeobox gene in aphakia mice.
@nl
P2093
P356
P1476
Deletion in the promoter regio ...... homeobox gene in aphakia mice.
@en
P2093
P304
P356
10.1093/HMG/9.11.1575
P577
2000-07-01T00:00:00Z