Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells.
about
An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stressCellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cellsStereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategyStructure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphatesOxidative damage is increased in human liver tissue adjacent to hepatocellular carcinomaInvolvement of oxidatively damaged DNA and repair in cancer development and aging.Cancer therapy. Targeting the poison within.Measurement of 7,8-dihydro-8-oxo-2'-deoxyguanosine metabolism in MCF-7 cells at low concentrations using accelerator mass spectrometry.Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1.Combustion products of 1,3-butadiene inhibit catalase activity and induce expression of oxidative DNA damage repair enzymes in human bronchial epithelial cellsHypoxia-inducible factor-1 modulates upregulation of mutT homolog-1 in colorectal cancer.Production, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements.Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma.Integrative genomic and gene expression analysis of chromosome 7 identified novel oncogene loci in non-small cell lung cancer.Chenodeoxycholic Acid Derivative HS-1200 Inhibits Hepatocarcinogenesis and Improves Liver Function in Diethylnitrosamine-Exposed Rats by Downregulating MTH1.Effects of silver nanoparticles on oxidative DNA damage-repair as a function of p38 MAPK status: a comparative approach using human Jurkat T cells and the nematode Caenorhabditis elegans.MutT-related proteins are novel progression and prognostic markers for colorectal cancer.A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.In silico prediction of new inhibitors for the nucleotide pool sanitizing enzyme, MTH1, using drug repurposing.The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions.MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?MutT homolog 1 counteracts the effect of anti-neoplastic treatments in adult and pediatric glioblastoma cells.
P2860
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P2860
Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Overexpression of hMTH1 mRNA: ...... e stress in lung cancer cells.
@en
Overexpression of hMTH1 mRNA: ...... e stress in lung cancer cells.
@nl
type
label
Overexpression of hMTH1 mRNA: ...... e stress in lung cancer cells.
@en
Overexpression of hMTH1 mRNA: ...... e stress in lung cancer cells.
@nl
prefLabel
Overexpression of hMTH1 mRNA: ...... e stress in lung cancer cells.
@en
Overexpression of hMTH1 mRNA: ...... e stress in lung cancer cells.
@nl
P2093
P2860
P1433
P1476
Overexpression of hMTH1 mRNA: ...... e stress in lung cancer cells.
@en
P2093
P2860
P356
10.1016/S0014-5793(98)00505-5
P407
P577
1998-06-01T00:00:00Z