GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
about
Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia.TGF-β contamination of purified recombinant GDF15.Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.BMPs as new insulin sensitizers: enhanced glucose uptake in mature 3T3-L1 adipocytes via PPARγ and GLUT4 upregulation.Exercise increases circulating GDF15 in humans.Structure and biophysical characterisation of the human full-length Neurturin-GFRa2 complex - a role for heparan sulfate in signalling.Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2.New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection.Reduced oxidative capacity in macrophages results in systemic insulin resistance.Moonlighting Activity of Secreted Inflammation-Regulatory Proteins.Binding of EphrinA5 to RET receptor tyrosine kinase: An in vitro study.CRP Stimulates GDF15 Expression in Endothelial Cells through p53.Presence of growth/differentiation factor-15 cytokine in human follicular fluid, granulosa cells, and oocytesRet and Substrate-Derived TGF-β Maverick Regulate Space-Filling Dendrite Growth in Drosophila Sensory NeuronsGDF15 Regulates Malat-1 Circular RNA and Inactivates NFκB Signaling Leading to Immune Tolerogenic DCs for Preventing Alloimmune Rejection in Heart TransplantationPathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic ApproachesGDF15 deficiency promotes high fat diet-induced obesity in mice
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GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh-hant
name
GFRAL is the receptor for GDF1 ...... obesity effects of the ligand.
@en
GFRAL is the receptor for GDF1 ...... obesity effects of the ligand.
@nl
type
label
GFRAL is the receptor for GDF1 ...... obesity effects of the ligand.
@en
GFRAL is the receptor for GDF1 ...... obesity effects of the ligand.
@nl
prefLabel
GFRAL is the receptor for GDF1 ...... obesity effects of the ligand.
@en
GFRAL is the receptor for GDF1 ...... obesity effects of the ligand.
@nl
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P921
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GFRAL is the receptor for GDF1 ...... obesity effects of the ligand.
@en
P2093
Anna Secher
Dennis Madsen
Jacob Fuglsbjerg Jeppesen
Jane Boesen Frantzen
Jishu Wang
Karin Hultman
Kristian T Hansen
Linda Yang
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P2888
P304
P356
10.1038/NM.4394
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P577
2017-08-28T00:00:00Z
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1091432239