about
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.The role of the PD-1 pathway in autoimmunity and peripheral toleranceVisualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice.T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction.Anti-CCL2 treatment inhibits Theiler's murine encephalomyelitis virus-induced demyelinating diseaseTolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns.Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity.Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity.Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade.Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.Repeated hapten exposure induces persistent tactile sensitivity in mice modeling localized provoked vulvodyniaCD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursorsEfficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment.Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor controlProgrammed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetesProgrammed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against AutoimmunityCutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD miceLandscape review of current HIV 'kick and kill' cure research - some kicking, not enough killing.Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection.Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation.Fractionated radiotherapy combined with PD-1 pathway blockade promotes CD8 T cell-mediated tumor clearance for the treatment of advanced malignanciesIsolation of Infiltrating Leukocytes from Mouse Skin Using Enzymatic Digest and Gradient Separation.PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetesT Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes.Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory.Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides.Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset.T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host diseaseEditorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes.Eradication of Established Tumors by Chemically Self-Assembled Nanoring Labeled T Cells.Immunoneutralization of chemokines for the prevention and treatment of central nervous system autoimmune diseaseChemokine Regulation of Immune-mediated Demyelinating DiseaseKeystone Symposia: chemokines and chemokine receptors. 16-21st February 2001, Taos, NM, USASelective CC chemokine receptor expression by central nervous system-infiltrating encephalitogenic T cells during experimental autoimmune encephalomyelitis
P50
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Brian T Fife
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Brian T Fife
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Brian T Fife
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Brian T Fife
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Brian T Fife
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type
label
Brian T Fife
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Brian T Fife
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Brian T Fife
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Brian T Fife
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Brian T Fife
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prefLabel
Brian T Fife
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Brian T Fife
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Brian T Fife
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Brian T Fife
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Brian T Fife
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P1053
D-2042-2013
P106
P21
P31
P3829
P496
0000-0001-9826-5637
P569
2000-01-01T00:00:00Z