A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect.
about
Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.Identification of novel pathogenic copy number aberrations in multiple myeloma: the Malaysian contextRoles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer.WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.CSNK1α1 mediates malignant plasma cell survival.The shaping and functional consequences of the dosage effect landscape in multiple myeloma.Expression profile of telomere-associated genes in multiple myeloma.Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma.A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias.Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation.The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma.Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.The molecular characterization and clinical management of multiple myeloma in the post-genome era.Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathwayFOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer.Foxl1 inhibits tumor invasion and predicts outcome in human renal cancerAntibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.Chromosome 1q21 gains confer inferior outcomes in multiple myeloma treated with bortezomib but copy number variation and percentage of plasma cells involved have no additional prognostic value.Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche.Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways.The use of molecular-based risk stratification and pharmacogenomics for outcome prediction and personalized therapeutic management of multiple myeloma.Genome-wide arrays in routine diagnostics of hematological malignancies.Molecular profiling of multiple myeloma: from gene expression analysis to next-generation sequencing.Non-coding RNA: a novel opportunity for the personalized treatment of multiple myeloma.Identification of the key genes connected with plasma cells of multiple myeloma using expression profiles.WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response.IQGAP1 Scaffold-MAP Kinase Interactions Enhance Multiple Myeloma Clonogenic Growth and Self-Renewal.Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo.Clinical fracture risk evaluated by hierarchical agglomerative clustering.A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity.Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms.SNP Array in Hematopoietic Neoplasms: A Review.Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line.Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis.Overexpression of RKIP and its cross-talk with several regulatory gene products in multiple myeloma.HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.The transcriptional profiling of human in vivo-generated plasma cells identifies selective imbalances in monoclonal gammopathiesRecurrent alterations of the WW domain containing oxidoreductase gene spanning the common fragile site FRA16D in multiple myeloma and monoclonal gammopathy of undetermined significance.High detection rate of clinically relevant genomic abnormalities in plasma cells enriched from patients with multiple myeloma.
P2860
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P2860
A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
A SNP microarray and FISH-base ...... als a wide gene dosage effect.
@en
A SNP microarray and FISH-base ...... als a wide gene dosage effect.
@nl
type
label
A SNP microarray and FISH-base ...... als a wide gene dosage effect.
@en
A SNP microarray and FISH-base ...... als a wide gene dosage effect.
@nl
prefLabel
A SNP microarray and FISH-base ...... als a wide gene dosage effect.
@en
A SNP microarray and FISH-base ...... als a wide gene dosage effect.
@nl
P2093
P50
P356
P1476
A SNP microarray and FISH-base ...... als a wide gene dosage effect.
@en
P2093
Adrian Andronache
Cristina Battaglia
Donata Verdelli
Giorgio Lambertenghi Deliliers
Luca Agnelli
Marta Lionetti
P304
P356
10.1002/GCC.20668
P577
2009-07-01T00:00:00Z