Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.
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Proteomic-Based Approaches for the Study of Cytokines in Lung CancerTherapeutic cancer vaccines: past, present, and futureCancer immunotherapyLentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populationsInnate and Adaptive Immune Regulation During Chronic Viral InfectionsMechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer ImmunotherapyChemo-immunotherapy with oxaliplatin and interleukin-7 inhibits colon cancer metastasis in miceARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune systemCD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help.Cytokines as Adjuvants for Vaccine and Cellular Therapies for Cancer.Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma.Systemic administration of TLR3 agonist induces IL-7 expression and IL-7-dependent CXCR3 ligand production in the lung.Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype.Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis.Memories that last forever: strategies for optimizing vaccine T-cell memory.Redirecting the immune response: role of adoptive T cell therapy.Abrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice.Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulationInterleukin-7, but not thymic stromal lymphopoietin, plays a key role in the T cell response to influenza A virus.Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression.NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments.Immunotherapeutic effects of IL-7 during a chronic viral infection in mice.Peptide-pulsed dendritic cells have superior ability to induce immune-mediated tissue destruction compared to peptide with adjuvantIL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.Interleukin-7 inhibits tumor-induced CD27-CD28- suppressor T cells: implications for cancer immunotherapy.T(H)17 cells in tumour immunity and immunotherapy.Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infectionImmunomodulatory and anticancer potential of Gan cao (Glycyrrhiza uralensis Fisch.) polysaccharides by CT-26 colon carcinoma cell growth inhibition and cytokine IL-7 upregulation in vitro.IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells.IL-7 receptor α blockade, an off-switch for autoreactive T cells.Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice.Anti-viral CD8 T cells and the cytokines that they loveImmunoregulation of hepatitis B virus infection--rationale and clinical applicationInterleukin-7 enhances the Th1 response to promote the development of Sjögren's syndrome-like autoimmune exocrinopathy in miceInterdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.Forced co-expression of IL-21 and IL-7 in whole-cell cancer vaccines promotes antitumor immunity.Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.The polarization of immune cells in the tumour environment by TGFbeta.
P2860
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P2860
Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Adjuvant IL-7 antagonizes mult ...... ks to enhance immunotherapies.
@en
Adjuvant IL-7 antagonizes mult ...... ks to enhance immunotherapies.
@nl
type
label
Adjuvant IL-7 antagonizes mult ...... ks to enhance immunotherapies.
@en
Adjuvant IL-7 antagonizes mult ...... ks to enhance immunotherapies.
@nl
prefLabel
Adjuvant IL-7 antagonizes mult ...... ks to enhance immunotherapies.
@en
Adjuvant IL-7 antagonizes mult ...... ks to enhance immunotherapies.
@nl
P2093
P2860
P50
P356
P1433
P1476
Adjuvant IL-7 antagonizes mult ...... ks to enhance immunotherapies.
@en
P2093
Alisha R Elford
Arda Shahinian
Brigitte Assouline
Dilan Dissanayake
Katharina Lahl
Linh T Nguyen
Matthew A Gronski
Michel Morre
Salim Dhanji
P2860
P2888
P304
P356
10.1038/NM.1953
P407
P577
2009-04-26T00:00:00Z