Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. - Wikidata - wikimedia - TriplyDB

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

http://www.wikidata.org/entity/Q47960215

about

PPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancer Phosphorylation of the PTEN tail regulates protein stability and function Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex Novel repressor regulates insulin sensitivity through interaction with Foxo1 The PI3K-PDK1 connection: more than just a road to PKB Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)Forkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed mice DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B Regulation of glucose metabolism from a liver-centric perspective Obesity and cancer, a case for insulin signaling FoxO Transcription Factors and Regenerative Pathways in Diabetes Mellitus FOXO transcription factors throughout T cell biology mTOR-dependent cell survival mechanisms Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change Forkhead box transcription factor 1: role in the pathogenesis of diabetic cardiomyopathy The critical role of Akt in cardiovascular function Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family Neutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1 Estrogen regulation of Pak1 and FKHR pathways in breast cancer cells Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis A brief introduction to FOXOlogy Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure.Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival.Identification and analysis of evolutionary selection pressures acting at the molecular level in five forkhead subfamilies.

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P2860

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

http://www.wikidata.org/entity/Q47960215

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

@zh-cn

1999年学术文章

@zh-hans

1999年学术文章

@zh-my

1999年学术文章

@zh-sg

1999年學術文章

@yue

1999年學術文章

@zh-hant

name

Insulin stimulates phosphoryla ...... Wortmannin-sensitive pathway.

@en

Insulin stimulates phosphoryla ...... Wortmannin-sensitive pathway.

@nl

type

label

Insulin stimulates phosphoryla ...... Wortmannin-sensitive pathway.

@en

Insulin stimulates phosphoryla ...... Wortmannin-sensitive pathway.

@nl

prefLabel

Insulin stimulates phosphoryla ...... Wortmannin-sensitive pathway.

@en

Insulin stimulates phosphoryla ...... Wortmannin-sensitive pathway.

@nl

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P356

JBC.274.23.15982

P1433

Journal of Biological Chemistry

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Insulin stimulates phosphoryla ...... Wortmannin-sensitive pathway.

@en

P2093

Accili D

http://www.w3.org/2001/XMLSchema#string

Nakae J

http://www.w3.org/2001/XMLSchema#string

Park BC

http://www.w3.org/2001/XMLSchema#string

P2860

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

Signalling through the lipid products of phosphoinositide-3-OH kinase

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

The IRS-signalling system: a network of docking proteins that mediate insulin action

Immunopharmacology of rapamycin

Identification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYN

P304

15982-15985

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scholarly article

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10.1074/JBC.274.23.15982

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23

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274

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1999-06-01T00:00:00Z

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P921

phosphorylation