ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis.
about
Caspases: the executioners of apoptosisStructure and physiological function of calpainsThe c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspasesA novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness scoreDentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosisCaspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tractFas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signalingThe CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin AProteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosisCaspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosisCaspase-mediated cleavage of p130cas in etoposide-induced apoptotic Rat-1 cells.The cellular protein PRA1 modulates the anti-apoptotic activity of Epstein-Barr virus BHRF1, a homologue of Bcl-2, through direct interaction.Predominant identification of RNA-binding proteins in Fas-induced apoptosis by proteome analysis.Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death.Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival.Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosisCaspases and neurodegeneration: on the cutting edge of new therapeutic approaches.Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells.Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitorsUric acid promotes apoptosis in human proximal tubule cells by oxidative stress and the activation of NADPH oxidase NOX 4.HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells.Monitoring caspase activity in living cells using fluorescent proteins and flow cytometry.A miniaturized device for bioluminescence analysis of caspase-3/7 activity in a single apoptotic cell.Implication of caspase-3 and granzyme B expression and activity in spleenocytes of ehrlich ascites carcinoma mice subjected to immunotherapyThe ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type.The role of matrix degrading enzymes and apoptosis in rupture of membranes.Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.Regulation of caspase activation in apoptosis: implications for transformation and drug resistance.Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin.The baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent pathwaySystemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death.Activation of CPP32-like proteases is not sufficient to trigger apoptosis: inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity.Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis.Noninvasive imaging of apoptosis and its application in cancer therapeutics.Differential suppression by protease inhibitors and cytokines of apoptosis induced by wild-type p53 and cytotoxic agentsActivation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B.Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32.HIV-1 kills renal tubular epithelial cells in vitro by triggering an apoptotic pathway involving caspase activation and Fas upregulationA kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.A triggered-suicide system designed as a defense against bacteriophages.
P2860
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P2860
ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
ICE/CED3-like proteases as the ...... ol of inappropriate apoptosis.
@en
ICE/CED3-like proteases as the ...... ol of inappropriate apoptosis.
@nl
type
label
ICE/CED3-like proteases as the ...... ol of inappropriate apoptosis.
@en
ICE/CED3-like proteases as the ...... ol of inappropriate apoptosis.
@nl
prefLabel
ICE/CED3-like proteases as the ...... ol of inappropriate apoptosis.
@en
ICE/CED3-like proteases as the ...... ol of inappropriate apoptosis.
@nl
P2860
P356
P1433
P1476
ICE/CED3-like proteases as the ...... ol of inappropriate apoptosis.
@en
P2093
Nicholson DW
P2860
P2888
P304
P356
10.1038/NBT0396-297
P577
1996-03-01T00:00:00Z