Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death.
about
Caspases: the executioners of apoptosisAn NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activityCD95-Mediated murine hepatic apoptosis requires an intact glutathione statusEffect of hepatocyte apoptosis induced by TNF-alpha on acute severe hepatitis in mouse modelsGalectin-9 ameliorates Con A-induced hepatitis by inducing CD4(+)CD25(low/int) effector T-Cell apoptosis and increasing regulatory T cell number.Modulation of platelet caspases and life-span by anti-platelet antibodies in mice.Pretreatment with pancaspase inhibitor (Z-VAD-FMK) delays but does not prevent intraperitoneal heat-killed group B Streptococcus-induced preterm delivery in a pregnant mouse modelPlasmacytoid dendritic cells control lung inflammation and monocyte recruitment in indirect acute lung injury in miceRegulation of caspase activation in apoptosis: implications in pathogenesis and treatment of disease.Gene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling.Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis.Activation of apoptosis and its inhibition.Effects of a caspase and a calpain inhibitor on resting energy expenditures in normal and hypermetabolic rats: a pilot studyProtective effects of HFE7A, mouse anti-human/mouse Fas monoclonal antibody against acute and lethal hepatic injury induced by Jo2[18F]- and [11C]-labeled N-benzyl-isatin sulfonamide analogues as PET tracers for apoptosis: synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98.Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: introduction of a hydrophilic group increases potency in a whole cell assayMX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activityEffects of minocycline on Fas-mediated fulminant hepatitis in miceApoptosis in hepatitis C virus infection.Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis.Mechanisms of indirect acute lung injury: a novel role for the coinhibitory receptor, programmed death-1.Intracerebroventricular injection of anti-Fas activates the hypothalamus-pituitary-adrenal axis and induces peripheral interleukin-6 and serum amyloid A in mice: comparison with other ligands of the tumor necrosis factor/nerve growth factor receptorApoptosis-based therapies and drug targets.On the TRAIL of a new therapy for leukemia.Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates.The Fas counterattack: a molecular mechanism of tumor immune privilege.Fas-mediated suicide of tumor-reactive T cells following activation by specific tumor: selective rescue by caspase inhibitionNitrosothiols in the immune system: signaling and protection.Prevention of lymphocyte cell death in sepsis improves survival in mice.Lymphocytes in the development of lung inflammation: a role for regulatory CD4+ T cells in indirect pulmonary lung injury.Novel Death Defying Domain in Met entraps the active site of caspase-3 and blocks apoptosis in hepatocytes.Bcl-2 overexpression in type II epithelial cells does not prevent hyperoxia-induced acute lung injury in mice.Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant.beta(2)-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein.Non-specific effects of methyl ketone peptide inhibitors of caspases.Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line.Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.Protection from lethal apoptosis in lipopolysaccharide-induced acute lung injury in mice by a caspase inhibitor.Lysosomes and Fas-mediated liver cell deathDual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways.
P2860
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P2860
Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Systemic injection of a tripep ...... t liver destruction and death.
@ast
Systemic injection of a tripep ...... t liver destruction and death.
@en
type
label
Systemic injection of a tripep ...... t liver destruction and death.
@ast
Systemic injection of a tripep ...... t liver destruction and death.
@en
prefLabel
Systemic injection of a tripep ...... t liver destruction and death.
@ast
Systemic injection of a tripep ...... t liver destruction and death.
@en
P2093
P2860
P356
P1476
Systemic injection of a tripep ...... t liver destruction and death.
@en
P2093
P2860
P304
P356
10.1084/JEM.184.5.2067
P407
P577
1996-11-01T00:00:00Z